Akebia Therapeutics, Inc(NASDAQ:AKBA) 
Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of renal therapeutics for patients with kidney diseases. The company's lead product investigational product candidate is vadadustat, an oral therapy, which is in Phase III development for the tre...
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Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenues | ||||||||||||||||||||||||||||||||||||||||||||||||
product revenue | 51,992,000 | 54,291,000 | 56,789,000 | 60,461,000 | 55,791,000 | 44,370,000 | 35,592,000 | 41,209,000 | 31,009,000 | 53,233,000 | 40,118,000 | 42,244,000 | 34,828,000 | 49,677,000 | 42,239,000 | 43,703,000 | 41,448,000 | 42,096,000 | 36,753,000 | 32,959,000 | 30,408,000 | 34,604,000 | 34,392,000 | 30,696,000 | 29,209,000 | 28,915,000 | 30,004,000 | 29,089,000 | 23,111,000 | |||||||||||||||||||
license, collaboration and other revenue | 1,552,000 | 3,331,000 | 1,977,000 | 2,011,000 | 1,545,000 | 2,127,000 | 1,836,000 | 2,439,000 | 1,598,000 | 2,963,000 | 1,928,000 | 14,132,000 | 5,299,000 | 5,503,000 | 6,725,000 | 83,056,000 | 20,251,000 | 17,509,000 | 12,003,000 | 19,954,000 | 21,896,000 | 22,095,000 | 25,596,000 | 59,446,000 | 59,269,000 | 40,640,000 | 61,973,000 | 71,714,000 | 49,555,000 | |||||||||||||||||||
total revenues | 53,544,000 | 57,622,000 | 58,766,000 | 62,472,000 | 57,336,000 | 46,497,000 | 37,428,000 | 43,648,000 | 32,607,000 | 56,196,000 | 42,046,000 | 56,376,000 | 40,127,000 | 55,180,000 | 48,964,000 | 126,759,000 | 61,699,000 | 59,605,000 | 48,756,000 | 52,913,000 | 52,304,000 | 56,699,000 | 59,988,000 | 90,142,000 | 88,478,000 | 69,555,000 | 91,977,000 | 100,803,000 | 72,666,000 | |||||||||||||||||||
yoy | -6.61% | 23.93% | 57.01% | 43.13% | 75.84% | -17.26% | -10.98% | -22.58% | -18.74% | 1.84% | -14.13% | -55.53% | -34.96% | -7.42% | 0.43% | 139.56% | 17.96% | 5.13% | -18.72% | -41.30% | -40.88% | -18.48% | -34.78% | -10.58% | 21.76% | |||||||||||||||||||||||
qoq | -7.08% | -1.95% | -5.93% | 8.96% | 23.31% | 24.23% | -14.25% | 33.86% | -41.98% | 33.65% | -25.42% | 40.49% | -27.28% | 12.70% | -61.37% | 105.45% | 3.51% | 22.25% | -7.86% | 1.16% | -7.75% | -5.48% | -33.45% | 1.88% | 27.21% | -24.38% | -8.76% | 38.72% | ||||||||||||||||||||
cost of goods sold | ||||||||||||||||||||||||||||||||||||||||||||||||
cost of product and other revenue | 12,290,000 | 12,535,000 | 9,383,000 | 9,919,000 | 7,625,000 | 11,355,000 | 5,150,000 | 8,036,000 | 2,594,000 | |||||||||||||||||||||||||||||||||||||||
total cost of goods sold | 12,290,000 | 12,535,000 | 9,383,000 | 9,919,000 | 7,625,000 | 20,365,000 | 14,161,000 | 17,047,000 | 11,605,000 | 18,665,000 | 18,009,000 | 17,284,000 | 19,484,000 | -3,095,000 | 37,947,000 | 18,600,000 | 31,344,000 | 50,350,000 | 15,944,000 | 52,495,000 | 34,606,000 | 63,234,000 | 30,345,000 | 174,616,000 | 27,713,000 | 38,147,000 | 38,263,000 | 37,669,000 | 31,257,000 | |||||||||||||||||||
operating expenses: | ||||||||||||||||||||||||||||||||||||||||||||||||
research and development | 14,807,000 | 26,648,000 | 14,944,000 | 11,013,000 | 9,754,000 | 11,786,000 | 8,487,000 | 7,647,000 | 9,731,000 | 9,865,000 | 13,330,000 | 20,197,000 | 19,686,000 | 31,904,000 | 27,350,000 | 26,027,000 | 43,833,000 | 29,556,000 | 40,471,000 | 37,214,000 | 40,611,000 | 37,578,000 | 46,857,000 | 52,819,000 | 81,231,000 | 80,412,000 | 74,512,000 | 85,694,000 | 82,351,000 | 87,052,000 | 70,634,000 | 71,917,000 | 61,404,000 | 68,382,000 | 58,711,000 | 43,751,000 | 60,049,000 | 33,435,000 | 31,238,000 | 30,877,000 | 20,235,000 | 15,790,000 | 7,182,000 | 7,505,000 | 7,068,000 | 6,648,000 | 5,524,895 | 6,157,928 |
selling, general and administrative | 30,436,000 | 26,089,000 | 29,094,000 | 26,555,000 | 25,742,000 | 27,675,000 | 26,516,000 | 26,917,000 | 25,438,000 | 25,436,000 | 22,710,000 | 27,036,000 | 25,221,000 | 30,647,000 | 30,918,000 | 32,807,000 | 44,327,000 | 44,825,000 | 46,357,000 | 41,651,000 | 41,328,000 | 40,311,000 | 40,171,000 | 35,482,000 | 37,983,000 | 44,918,000 | 34,178,000 | 36,068,000 | 34,291,000 | |||||||||||||||||||
license | 707,000 | 903,000 | 896,000 | 896,000 | 701,000 | 978,000 | 769,000 | 762,000 | 711,000 | |||||||||||||||||||||||||||||||||||||||
total operating expenses | 45,950,000 | 53,640,000 | 44,934,000 | 38,464,000 | 36,197,000 | 40,439,000 | 35,772,000 | 35,326,000 | 35,938,000 | 36,157,000 | 37,073,000 | 48,088,000 | 45,581,000 | 64,625,000 | 59,191,000 | 74,257,000 | 88,848,000 | 75,410,000 | 87,698,000 | 79,759,000 | 82,634,000 | 78,868,000 | 87,738,000 | 89,345,000 | 119,890,000 | 126,299,000 | 109,619,000 | 122,657,000 | 117,378,000 | 142,240,000 | 81,012,000 | 84,455,000 | 70,428,000 | 75,949,000 | 65,459,000 | 50,656,000 | 65,837,000 | 39,579,000 | 36,182,000 | 36,188,000 | 26,046,000 | 19,678,000 | 10,889,000 | 10,896,000 | 10,607,000 | 9,584,000 | 7,839,996 | 9,909,247 |
income from operations | -4,696,000 | -8,553,000 | 4,449,000 | 14,089,000 | 13,514,000 | -14,307,000 | -12,505,000 | -8,725,000 | -14,936,000 | 1,374,000 | -13,036,000 | |||||||||||||||||||||||||||||||||||||
yoy | -134.75% | -40.22% | -135.58% | -261.48% | -190.48% | -1141.27% | -4.07% | |||||||||||||||||||||||||||||||||||||||||
qoq | -45.10% | -292.25% | -68.42% | 4.25% | -194.46% | 14.41% | 43.32% | -41.58% | -1187.05% | -110.54% | ||||||||||||||||||||||||||||||||||||||
operating margin % | -8.77% | -14.84% | 7.57% | 22.55% | 23.57% | -30.77% | -33.41% | -19.99% | -45.81% | 2.45% | -31.00% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% |
other income | 3,000 | -117,000 | -10,000 | -28,000 | 213,000 | 55,000 | -17,000 | -39,000 | 95,000 | 658,000 | -43,000 | -10,000 | 282,000 | 434,000 | 1,167,000 | 411,000 | 1,134,000 | 560,000 | 427,000 | 1,265,000 | 161,000 | 720,000 | 410,000 | 376,000 | 350,000 | -554,000 | -185,000 | 23,000 | -78,000 | 29,000 | 16,000 | 32,000 | 4,000 | 200,000 | 10,000 | -6,000 | 3,000 | -345,000 | 139,000 | 14,000 | ||||||||
interest expense | -4,691,000 | -4,827,000 | -4,748,000 | -6,834,000 | -7,770,000 | -6,877,000 | -6,661,000 | -2,149,000 | -2,498,000 | -1,418,000 | -1,410,000 | -1,642,000 | -1,561,000 | -3,512,750 | -3,952,000 | -5,037,000 | -5,062,000 | -3,713,250 | -5,085,000 | -4,962,000 | -4,805,000 | |||||||||||||||||||||||||||
change in fair value of warrant liability | 456,000 | 2,262,000 | 1,464,000 | -6,980,000 | 155,000 | -1,675,000 | -856,000 | 2,331,000 | -129,000 | |||||||||||||||||||||||||||||||||||||||
income before income taxes | -8,928,000 | -11,235,000 | 1,155,000 | |||||||||||||||||||||||||||||||||||||||||||||
income tax expense | -126,000 | -1,009,000 | -615,000 | |||||||||||||||||||||||||||||||||||||||||||||
net income | -9,054,000 | -12,244,000 | 540,000 | 247,000 | 6,112,000 | -22,804,000 | -20,039,000 | -8,582,000 | -17,985,000 | 614,000 | -14,489,000 | -11,172,000 | -26,217,000 | -7,552,000 | -51,865,000 | 29,276,000 | -62,421,000 | -70,678,000 | -59,544,000 | -83,038,000 | -69,580,000 | -87,000,000 | -59,959,000 | -175,751,000 | -60,747,000 | -94,483,000 | -54,585,000 | -58,170,000 | -72,421,000 | -60,054,000 | -26,047,000 | -34,069,000 | -23,418,000 | 12,280,000 | -23,134,000 | -21,518,000 | -44,543,000 | -37,862,000 | -36,308,000 | -35,779,000 | -25,798,000 | -19,475,000 | -10,689,000 | -10,695,000 | -10,370,000 | -9,348,000 | -7,618,327 | -9,697,110 |
yoy | -248.13% | -46.31% | -102.69% | -102.88% | -133.98% | -3814.01% | 38.30% | -23.18% | -31.40% | -108.13% | -72.06% | -138.16% | -58.00% | -89.31% | -12.90% | -135.26% | -10.29% | -18.76% | -0.69% | -52.75% | 14.54% | -7.92% | 9.85% | 202.13% | -16.12% | 57.33% | 109.56% | 70.74% | 209.25% | -589.04% | 12.59% | 58.33% | -47.43% | -132.43% | -36.28% | -39.86% | 72.66% | 94.41% | 239.68% | 234.54% | 148.78% | 108.33% | 40.31% | 10.29% | ||||
qoq | -26.05% | -2367.41% | 118.62% | -95.96% | -126.80% | 13.80% | 133.50% | -52.28% | -3029.15% | -104.24% | 29.69% | -57.39% | 247.15% | -85.44% | -277.16% | -146.90% | -11.68% | 18.70% | -28.29% | 19.34% | -20.02% | 45.10% | -65.88% | 189.32% | -35.71% | 73.09% | -6.16% | -19.68% | 20.59% | 130.56% | -23.55% | 45.48% | -290.70% | -153.08% | 7.51% | -51.69% | 17.65% | 4.28% | 1.48% | 38.69% | 32.47% | 82.20% | -0.06% | 3.13% | 10.93% | 22.70% | -21.44% | |
net income margin % | -16.91% | -21.25% | 0.92% | 0.40% | 10.66% | -49.04% | -53.54% | -19.66% | -55.16% | 1.09% | -34.46% | -19.82% | -65.34% | -13.69% | -105.92% | 23.10% | -101.17% | -118.58% | -122.13% | -156.93% | -133.03% | -153.44% | -99.95% | -194.97% | -68.66% | -135.84% | -59.35% | -57.71% | -99.66% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% |
comprehensive income | -9,054,000 | 1,724,750 | 540,000 | 247,000 | 6,112,000 | -11,172,000 | ||||||||||||||||||||||||||||||||||||||||||
net income per share | -0.14 | -0.04 | -0.28 | 0.16 | -0.35 | -0.4 | -0.34 | -0.51 | -0.45 | -0.59 | -0.42 | -1.28 | -0.47 | -0.79 | -0.46 | -0.49 | -0.62 | -0.93 | -0.46 | -0.6 | -0.48 | 0.34 | -0.49 | -0.53 | -1.15 | -0.99 | -0.96 | -0.95 | -0.7 | -0.68 | -0.4 | -0.53 | 0.12 | -0.47 | -0.39 | -43.37 | ||||||||||||
basic | -0.03 | 0.008 | 0.03 | -0.06 | ||||||||||||||||||||||||||||||||||||||||||||
diluted | -0.03 | 0.008 | 0.03 | -0.06 | ||||||||||||||||||||||||||||||||||||||||||||
weighted-average shares of common stock outstanding: | ||||||||||||||||||||||||||||||||||||||||||||||||
basic | 267,046,755 | 264,786,432 | 262,565,500 | 235,497,720 | 186,817,431 | |||||||||||||||||||||||||||||||||||||||||||
diluted | 267,046,755 | 274,372,722 | 271,104,020 | 241,602,853 | 186,817,431 | |||||||||||||||||||||||||||||||||||||||||||
amortization of intangible asset | 9,010,000 | 9,011,000 | 9,011,000 | 9,011,000 | 9,010,000 | 9,011,000 | 9,011,000 | |||||||||||||||||||||||||||||||||||||||||
restructuring | 58,000 | 169,000 | -94,000 | 106,000 | 1,222,000 | 180,000 | 14,531,000 | |||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | -517,000 | -906,000 | ||||||||||||||||||||||||||||||||||||||||||||||
net income before income taxes | 247,000 | 6,112,000 | ||||||||||||||||||||||||||||||||||||||||||||||
weighted-average common shares outstanding: | ||||||||||||||||||||||||||||||||||||||||||||||||
basic | 267,046,755 | 264,786,432 | 262,565,500 | 235,497,720 | 186,817,431 | |||||||||||||||||||||||||||||||||||||||||||
diluted | 267,046,755 | 274,372,722 | 271,104,020 | 241,602,853 | 186,817,431 | |||||||||||||||||||||||||||||||||||||||||||
loss on termination of lease | ||||||||||||||||||||||||||||||||||||||||||||||||
net loss before income taxes | -22,804,000 | -20,039,000 | -8,582,000 | -17,985,000 | -87,000,000 | -59,959,000 | -175,751,000 | -60,747,000 | -96,235,000 | -55,862,000 | -59,015,000 | -75,178,000 | ||||||||||||||||||||||||||||||||||||
comprehensive loss | -22,804,000 | -20,039,000 | -8,582,000 | -17,985,000 | 614,000 | -14,489,000 | -21,593 | -44,722 | -37,897 | -36,352 | -35,716 | -25,824 | -19,455 | -10,708 | -10,703 | -10,374 | -9,391 | -7,626,543 | ||||||||||||||||||||||||||||||
net income per share | -0.14 | -0.04 | -0.28 | 0.16 | -0.35 | -0.4 | -0.34 | -0.51 | -0.45 | -0.59 | -0.42 | -1.28 | -0.47 | -0.79 | -0.46 | -0.49 | -0.62 | -0.93 | -0.46 | -0.6 | -0.48 | 0.34 | -0.49 | -0.53 | -1.15 | -0.99 | -0.96 | -0.95 | -0.7 | -0.68 | -0.4 | -0.53 | 0.12 | -0.47 | -0.39 | -43.37 | ||||||||||||
basic and diluted | -0.11 | -0.1 | -0.04 | -0.09 | -0.08 | |||||||||||||||||||||||||||||||||||||||||||
weighted-average common shares outstanding: | ||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted | 257,157,782 | 210,946,658 | 210,348,459 | 209,705,397 | 204,955,151 | 187,465,448 | 188,306,350 | |||||||||||||||||||||||||||||||||||||||||
product | 7,113,000 | 8,998,000 | 8,273,000 | 10,473,000 | -12,105,000 | 28,936,000 | 9,589,000 | 22,333,000 | 41,340,000 | 6,933,000 | 43,484,000 | 25,595,000 | 56,026,000 | 24,239,000 | 49,988,000 | 18,613,000 | 29,047,000 | 29,162,000 | 28,569,000 | 22,157,000 | ||||||||||||||||||||||||||||
license expense | 595,250 | 864,000 | 949,000 | 568,000 | 852,000 | 743,000 | 892,000 | 688,000 | 1,029,000 | 870,000 | 894,000 | 695,000 | 979,000 | 710,000 | 1,044,000 | 676,000 | 969,000 | 929,000 | 895,000 | 736,000 | ||||||||||||||||||||||||||||
operating income | -8,996,000 | -24,938,000 | -6,350,000 | -48,174,000 | 33,902,000 | -58,493,000 | -66,155,000 | -54,886,000 | -79,341,000 | -64,936,000 | -85,403,000 | -58,095,000 | -173,819,000 | -59,125,000 | -94,891,000 | -55,905,000 | -59,523,000 | -75,969,000 | -90,158,000 | -27,843,000 | -35,662,000 | -24,498,000 | 11,367,000 | -24,176,000 | -22,136,000 | -44,972,000 | -38,044,000 | -36,182,000 | -36,188,000 | -26,046,000 | -19,678,000 | -10,889,000 | -10,896,000 | -10,607,000 | -9,584,000 | -7,839,996 | -9,909,247 | |||||||||||
loss on lease termination | -524,000 | |||||||||||||||||||||||||||||||||||||||||||||||
revenues: | ||||||||||||||||||||||||||||||||||||||||||||||||
cost of goods sold: | ||||||||||||||||||||||||||||||||||||||||||||||||
amortization of intangibles | 9,011,000 | 9,010,000 | 9,011,000 | 9,011,000 | 9,011,000 | 9,010,000 | 9,011,000 | 9,011,000 | 9,011,000 | 7,208,000 | 6,106,000 | 9,101,000 | 9,100,000 | 6,825,250 | 9,101,000 | 9,100,000 | 9,100,000 | |||||||||||||||||||||||||||||||
other income: | ||||||||||||||||||||||||||||||||||||||||||||||||
net income per share | -0.14 | -0.04 | -0.28 | 0.16 | -0.35 | -0.4 | -0.34 | -0.51 | -0.45 | -0.59 | -0.42 | -1.28 | -0.47 | -0.79 | -0.46 | -0.49 | -0.62 | -0.93 | -0.46 | -0.6 | -0.48 | 0.34 | -0.49 | -0.53 | -1.15 | -0.99 | -0.96 | -0.95 | -0.7 | -0.68 | -0.4 | -0.53 | 0.12 | -0.47 | -0.39 | -43.37 | ||||||||||||
weighted-average number of common shares - basic and diluted | 184,768,983 | 182,782,680 | 183,882,446 | 179,599,045 | 165,949,695 | 173,782,151 | 161,329,990 | 153,820,809 | 138,463,152 | 143,314,729 | 136,906,968 | 128,395,163 | 118,395,919 | 118,863,063 | 118,268,832 | 117,063,352 | 58,038,252 | 57,027,598 | 56,890,295 | 48,613,565 | 43,500,795 | 46,938,618 | 40,819,957 | 38,759,221 | ||||||||||||||||||||||||
comprehensive loss: | ||||||||||||||||||||||||||||||||||||||||||||||||
total comprehensive loss | -26,217 | -7,552 | -51,865 | -62,421 | -70,678 | -59,544 | -83,041 | -69,584 | -86,993 | -59,944 | -175,760 | -60,747 | -94,489 | -54,602 | -58,111 | -72,196 | -59,906 | -25,997 | -33,978 | -23,526 | 12,061 | -23,061 | ||||||||||||||||||||||||||
other comprehensive loss - unrealized loss on debt securities | -3 | -4 | -108 | |||||||||||||||||||||||||||||||||||||||||||||
weighted-average number of common shares - basic | 183,597,766 | |||||||||||||||||||||||||||||||||||||||||||||||
weighted-average number of common shares - diluted | 190,375,317 | |||||||||||||||||||||||||||||||||||||||||||||||
comprehensive income: | ||||||||||||||||||||||||||||||||||||||||||||||||
total comprehensive income | 29,276 | |||||||||||||||||||||||||||||||||||||||||||||||
impairment of intangible asset | 115,527,000 | |||||||||||||||||||||||||||||||||||||||||||||||
other comprehensive gain - unrealized gain on debt securities | -1.75 | 1.5 | 15 | -9 | 66.75 | -17 | 59 | 225 | 8.25 | 50 | 91 | |||||||||||||||||||||||||||||||||||||
interest income | -2,317,000 | -2,274,000 | -2,308,000 | -1,972,000 | -790,000 | 228,000 | 485,000 | 869,000 | 1,737,000 | 1,780,000 | 1,561,000 | 1,076,000 | 913,000 | 842,000 | 608,000 | 435,000 | 179,000 | 219,000 | 270,000 | 234,000 | 139,000 | 116,000 | 96,000 | 81,000 | 56,000 | 50,442 | 19,025 | |||||||||||||||||||||
benefit from income taxes | -1,752,000 | -1,277,000 | -845,000 | -2,757,000 | ||||||||||||||||||||||||||||||||||||||||||||
collaboration revenue | 36,973,000 | 53,169,000 | 48,793,000 | 45,930,000 | 87,316,000 | 41,283,000 | 28,520,000 | 20,865,000 | ||||||||||||||||||||||||||||||||||||||||
general and administrative | 7,985,000 | 10,378,000 | 12,538,000 | 9,024,000 | 7,567,000 | 6,748,000 | 6,905,000 | 5,788,000 | 6,144,000 | 4,944,000 | 5,311,000 | 5,811,000 | 3,888,000 | 3,707,000 | 3,391,000 | 3,539,000 | 2,936,000 | 2,315,101 | 3,751,319 | |||||||||||||||||||||||||||||
other comprehensive gain - unrealized gain on securities | -45.25 | 73 | ||||||||||||||||||||||||||||||||||||||||||||||
other comprehensive loss - unrealized loss on securities | -75 | -179 | -26 | 20 | ||||||||||||||||||||||||||||||||||||||||||||
weighted-average number of common shares used in net loss per share applicable to common stockholders—basic and diluted | 37,716,949 | 37,897,902 | 37,811,056 | 36,873,594 | 28,784,231 | 26,614,671 | 20,030,129 | 15,406,386 | 19,691,167 | |||||||||||||||||||||||||||||||||||||||
other comprehensive income - unrealized gain on securities | -35 | -44 | 63 | |||||||||||||||||||||||||||||||||||||||||||||
reimbursements from aerpio | 64,000 | 84,000 | 105,000 | 156,000 | 180,000 | 171,227 | 193,112 | |||||||||||||||||||||||||||||||||||||||||
reconciliation of net loss to net loss applicable to common stockholders: | ||||||||||||||||||||||||||||||||||||||||||||||||
accretion on preferred stock | -86,899,555 | |||||||||||||||||||||||||||||||||||||||||||||||
net loss applicable to common stockholders | -19,475,000 | -10,689,000 | -10,695,000 | -10,370,000 | -9,348,000 | -7,618,327 | -96,596,665 | |||||||||||||||||||||||||||||||||||||||||
other comprehensive loss: | ||||||||||||||||||||||||||||||||||||||||||||||||
unrealized loss on securities | -19 | -8 | -4 | -43 | ||||||||||||||||||||||||||||||||||||||||||||
extinguishment of debt and other liabilities | ||||||||||||||||||||||||||||||||||||||||||||||||
revenue | ||||||||||||||||||||||||||||||||||||||||||||||||
weighted-average number of common shares used in net loss per share applicable to common stockholders’—basic and diluted | 19,652,056 | 2,227,058 | ||||||||||||||||||||||||||||||||||||||||||||||
other comprehensive loss, net of deferred tax: | ||||||||||||||||||||||||||||||||||||||||||||||||
unrealized loss on securities, net of tax of 0 | -8,216 | |||||||||||||||||||||||||||||||||||||||||||||||
grant income | ||||||||||||||||||||||||||||||||||||||||||||||||
gain on cancellation of preferred stock future tranche rights | ||||||||||||||||||||||||||||||||||||||||||||||||
net loss and comprehensive loss | -9,697,110 | |||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of preferred stock |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | ||||||||||||||||||||||||||||||||||||||||||||||||
current assets: | ||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents | 162,644,000 | 184,844,000 | 166,444,000 | 137,308,000 | 113,374,000 | 51,870,000 | 34,019,000 | 39,499,000 | 41,961,000 | 42,925,000 | 46,529,000 | 56,953,000 | 90,466,000 | 144,761,000 | 143,893,000 | 174,562,000 | 149,800,000 | 207,204,000 | 246,992,000 | 252,765,000 | 228,698,000 | 169,286,000 | 245,406,000 | 115,374,000 | 147,449,000 | 122,886,000 | 87,212,000 | 62,741,000 | 104,644,000 | 162,430,000 | 163,526,000 | 158,171,000 | 70,156,000 | 89,599,000 | 125,390,000 | 87,250,000 | 187,335,000 | 65,830,000 | 46,177,000 | 43,439,000 | 66,712,000 | 76,248,000 | 27,887,000 | 32,780,000 | 49,668,000 | 95,394,102 | 126,319,457 | |
inventories | 12,996,000 | 15,610,000 | 18,643,000 | 16,708,000 | 19,732,000 | 16,243,000 | 20,493,000 | 23,872,000 | 25,532,000 | 15,691,000 | 18,442,000 | 36,272,000 | ||||||||||||||||||||||||||||||||||||
accounts receivable | 62,536,000 | 47,031,000 | 66,223,000 | 72,809,000 | 61,538,000 | 34,368,000 | 32,170,000 | 29,765,000 | 26,620,000 | 39,290,000 | 22,592,000 | 81,869,000 | 17,781,000 | 39,180,000 | 23,094,000 | 81,869,000 | 64,582,000 | 50,875,000 | 49,690,000 | 35,005,000 | 35,233,000 | 26,853,000 | 24,466,000 | 39,115,000 | 104,872,000 | 38,864,000 | 29,654,000 | 28,888,000 | 48,435,000 | 16,666,000 | 688,000 | 132,000 | 35,852,000 | 34,216,000 | 14,000 | 48,000 | 74,000 | 48,000 | 57,000 | 113,953 | 119,395 | |||||||
prepaid expenses and other current assets | 5,305,000 | 5,470,000 | 7,026,000 | 7,832,000 | 9,138,000 | 11,350,000 | 13,438,000 | 18,961,000 | 18,831,000 | 20,243,000 | 22,039,000 | 25,381,000 | 33,541,000 | 29,618,000 | 42,129,000 | 24,121,000 | 33,140,000 | 39,502,000 | 11,181,000 | 12,214,000 | 14,877,000 | 9,037,000 | 10,035,000 | 8,656,000 | 6,626,000 | 7,754,000 | 28,606,000 | 15,554,000 | 15,724,000 | 6,694,000 | 5,162,000 | 8,100,000 | 6,348,000 | 3,952,000 | 11,174,000 | 3,248,000 | 2,155,000 | 3,825,000 | 3,873,000 | 2,505,000 | 1,324,000 | 2,125,000 | 2,288,000 | 1,514,000 | 1,445,000 | 1,691,312 | 1,468,165 | |
total current assets | 243,481,000 | 252,955,000 | 258,336,000 | 234,657,000 | 203,782,000 | 113,831,000 | 100,120,000 | 112,097,000 | 112,944,000 | 118,149,000 | 109,602,000 | 304,163,000 | 120,719,000 | 184,949,000 | 237,512,000 | 304,163,000 | 302,687,000 | 272,010,000 | 330,084,000 | 331,076,000 | 365,017,000 | 371,437,000 | 391,000,000 | 449,102,000 | 340,756,000 | 309,533,000 | 299,008,000 | 316,396,000 | 347,233,000 | 468,275,000 | 397,526,000 | 407,417,000 | 436,981,000 | 358,356,000 | 333,938,000 | 332,389,000 | 255,053,000 | 296,321,000 | 165,147,000 | 192,522,000 | 219,530,000 | 158,804,000 | 154,962,000 | 102,695,000 | 110,480,000 | 119,840,000 | 126,051,209 | 133,738,860 |
property and equipment | 956,000 | 1,222,000 | 1,473,000 | 1,714,000 | 1,904,000 | 2,200,000 | 2,533,000 | 2,895,000 | 3,265,000 | 3,629,000 | 4,023,000 | 4,816,000 | 5,214,000 | 5,622,000 | 6,035,000 | 6,451,000 | 6,754,000 | 7,196,000 | 7,670,000 | 8,168,000 | 8,622,000 | 8,821,000 | 9,380,000 | 9,855,000 | 10,380,000 | 12,799,000 | 10,903,000 | 9,512,000 | 8,023,000 | 3,808,000 | 3,726,000 | 3,714,000 | 3,617,000 | 3,364,000 | 2,934,000 | 2,904,000 | 2,612,000 | 2,688,000 | 1,832,000 | 629,000 | 479,000 | 398,000 | 404,000 | 210,000 | 205,000 | 181,029 | ||
operating right-of-use assets | 2,465,000 | 3,663,000 | 4,837,000 | 5,987,000 | 7,114,000 | 8,218,000 | 9,300,000 | 10,360,000 | 11,399,000 | 12,416,000 | 13,414,000 | |||||||||||||||||||||||||||||||||||||
goodwill | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 59,044,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | 55,053,000 | ||||||||||||||||||
other long-term assets | 56,574,000 | 59,681,000 | 40,462,000 | 44,193,000 | 38,341,000 | 37,377,000 | 27,134,000 | 17,779,000 | 11,793,000 | 12,423,000 | 3,862,000 | |||||||||||||||||||||||||||||||||||||
total assets | 362,520,000 | 376,565,000 | 364,152,000 | 345,595,000 | 310,185,000 | 220,670,000 | 207,142,000 | 220,196,000 | 225,477,000 | 241,703,000 | 234,998,000 | 521,804,000 | 276,858,000 | 351,830,000 | 435,894,000 | 521,804,000 | 535,356,000 | 525,550,000 | 602,267,000 | 611,863,000 | 628,703,000 | 644,139,000 | 676,143,000 | 745,174,000 | 787,719,000 | 771,201,000 | 795,220,000 | 823,528,000 | 890,793,000 | 996,540,000 | 403,826,000 | 413,781,000 | 442,713,000 | 364,247,000 | 338,589,000 | 336,822,000 | 259,256,000 | 300,216,000 | 169,118,000 | 195,635,000 | 221,440,000 | 159,588,000 | 155,665,000 | 103,459,000 | 110,995,000 | 120,170,000 | 126,357,583 | 134,028,409 |
liabilities and stockholders' equity | ||||||||||||||||||||||||||||||||||||||||||||||||
current liabilities: | ||||||||||||||||||||||||||||||||||||||||||||||||
accounts payable | 8,386,000 | 21,185,000 | 10,087,000 | 11,554,000 | 12,658,000 | 15,180,000 | 13,494,000 | 10,107,000 | 11,882,000 | 14,635,000 | 9,038,000 | 12,577,000 | 18,021,000 | 19,708,000 | 24,944,000 | 19,466,000 | 33,588,000 | 28,809,000 | 41,984,000 | 30,537,000 | 41,308,000 | 40,403,000 | 29,413,000 | 54,379,000 | 39,217,000 | 64,362,000 | 19,321,000 | 15,226,000 | 42,796,000 | 12,684,000 | 4,795,000 | 17,880,000 | 6,998,000 | 8,705,000 | 10,212,000 | 15,083,000 | 2,039,000 | 8,524,000 | 5,143,000 | 2,415,000 | 5,273,000 | 2,412,000 | 4,329,000 | 2,021,000 | 3,032,000 | 1,488,184 | 2,077,302 | |
accrued expenses and other current liabilities | 125,062,000 | 121,716,000 | 106,420,000 | 91,615,000 | 71,337,000 | 63,460,000 | 52,215,000 | 53,897,000 | 53,910,000 | 67,735,000 | 62,664,000 | 91,284,000 | 46,367,000 | 70,997,000 | 87,364,000 | 91,284,000 | 109,660,000 | 104,456,000 | 144,704,000 | 111,742,000 | 123,889,000 | 130,624,000 | 123,021,000 | 142,832,000 | 124,887,000 | 126,644,000 | 125,981,000 | 137,803,000 | ||||||||||||||||||||
current portion of deferred revenue | 4,496,000 | 3,881,000 | 5,532,000 | 1,241,000 | 43,296,000 | |||||||||||||||||||||||||||||||||||||||||||
current portion of long-term debt | 12,495,000 | 17,500,000 | 8,000,000 | 24,000,000 | 32,000,000 | 65,947,000 | 98,158,000 | 97,848,000 | 97,543,000 | |||||||||||||||||||||||||||||||||||||||
working capital fund liability, current portion | 23,445,000 | 17,356,000 | 12,991,000 | 10,016,000 | 5,991,000 | 2,274,000 | ||||||||||||||||||||||||||||||||||||||||||
total current liabilities | 173,884,000 | 162,938,000 | 133,379,000 | 118,717,000 | 91,227,000 | 80,914,000 | 65,709,000 | 107,300,000 | 66,487,000 | 99,870,000 | 79,702,000 | 233,680,000 | 82,944,000 | 124,756,000 | 187,965,000 | 233,680,000 | 253,914,000 | 256,493,000 | 189,205,000 | 165,595,000 | 172,679,000 | 187,146,000 | 181,458,000 | 195,774,000 | 214,152,000 | 208,118,000 | 223,148,000 | 185,618,000 | 202,613,000 | 265,693,000 | 177,399,000 | 164,420,000 | 151,419,000 | 144,349,000 | 151,357,000 | 181,591,000 | 133,463,000 | 114,268,000 | 26,139,000 | 20,932,000 | 13,409,000 | 14,166,000 | 5,903,000 | 8,841,000 | 6,885,000 | 6,522,000 | 4,769,716 | 6,123,220 |
long-term debt | 36,395,000 | 48,250,000 | 47,641,000 | 47,062,000 | 46,511,000 | 38,693,000 | 38,355,000 | 38,031,000 | 30,145,000 | 17,183,000 | 34,613,000 | 26,296,000 | 34,078,000 | 97,230,000 | 96,917,000 | 96,607,000 | 96,378,000 | 76,608,000 | 76,338,000 | 76,072,000 | 75,805,000 | |||||||||||||||||||||||||||
liability related to settlement royalties, net of current portion | 54,842,000 | 54,750,000 | 52,994,000 | 48,729,000 | 47,440,000 | 46,697,000 | ||||||||||||||||||||||||||||||||||||||||||
liability related to sale of future royalties, net of current portion | 50,414,000 | 50,608,000 | 50,576,000 | 51,082,000 | 51,549,000 | 52,066,000 | 52,381,000 | 53,101,000 | ||||||||||||||||||||||||||||||||||||||||
working capital fund liability, net of current portion | 16,405,000 | 22,606,000 | 27,726,000 | 30,556,000 | 34,420,000 | 38,013,000 | ||||||||||||||||||||||||||||||||||||||||||
warrant liability | 2,524,000 | 2,980,000 | 5,242,000 | 14,199,000 | 7,220,000 | 5,176,000 | 3,501,000 | 2,644,000 | 4,975,000 | |||||||||||||||||||||||||||||||||||||||
other long-term liabilities | 681,000 | 1,823,000 | 5,002,000 | 5,355,000 | 5,114,000 | 4,749,000 | 4,727,000 | 6,557,000 | 6,771,000 | 8,885,000 | 9,415,000 | |||||||||||||||||||||||||||||||||||||
total liabilities | 335,145,000 | 343,955,000 | 322,560,000 | 316,371,000 | 285,604,000 | 269,855,000 | 257,544,000 | 253,950,000 | 252,735,000 | 272,287,000 | 274,420,000 | 459,504,000 | 291,210,000 | 342,488,000 | 422,041,000 | 459,504,000 | 509,240,000 | 449,094,000 | 465,117,000 | 437,232,000 | 414,812,000 | 396,521,000 | 358,181,000 | 374,914,000 | 391,355,000 | 376,444,000 | 327,658,000 | 304,172,000 | 324,414,000 | 360,612,000 | 261,285,000 | 247,857,000 | 245,616,000 | 244,916,000 | 238,714,000 | 279,824,000 | 228,639,000 | 232,096,000 | 68,408,000 | 62,347,000 | 53,678,000 | 14,176,000 | 5,913,000 | 8,850,000 | 6,917,000 | 6,556,000 | 4,805,617 | 6,161,018 |
commitments and contingencies | ||||||||||||||||||||||||||||||||||||||||||||||||
stockholders' equity: | ||||||||||||||||||||||||||||||||||||||||||||||||
preferred stock 0.00001 par value... | ||||||||||||||||||||||||||||||||||||||||||||||||
common stock 0.00001 par value... | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 2,000 | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | |||||||||||||||||||||||||||
additional paid-in capital | 1,720,126,000 | 1,716,307,000 | 1,713,045,000 | 1,701,217,000 | 1,696,821,000 | 1,629,167,000 | 1,605,146,000 | 1,601,755,000 | 1,599,669,000 | 1,578,358,000 | 1,570,134,000 | 1,564,770,000 | 1,562,247,000 | 1,559,206,000 | 1,555,788,000 | 1,548,880,000 | 1,536,800,000 | 1,526,815,000 | 1,504,752,000 | 1,460,971,000 | 1,425,115,000 | 1,408,466,000 | 1,400,820,000 | 1,251,164,000 | 1,188,810,000 | 1,167,126,000 | 1,164,318,000 | 1,153,230,000 | 1,150,583,000 | 597,290,000 | 594,676,000 | 591,871,000 | 493,823,000 | 486,386,000 | 420,448,000 | 372,475,000 | 365,298,000 | 359,991,000 | 356,217,000 | 355,138,000 | 287,113,000 | 271,998,000 | 206,146,000 | 204,969,000 | 204,048,000 | 202,535,864 | 201,203,384 | |
accumulated other comprehensive income | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 23,000 | -442,000 | -42,000 | 37,000 | ||||||||||||||||||||||||||||||||
accumulated deficit | -1,692,759,000 | -1,683,705,000 | -1,671,461,000 | -1,672,001,000 | -1,672,248,000 | -1,678,360,000 | -1,655,556,000 | -1,635,517,000 | -1,626,935,000 | -1,608,950,000 | -1,609,564,000 | -1,493,496,000 | -1,579,130,000 | -1,552,913,000 | -1,545,361,000 | -1,493,496,000 | -1,522,772,000 | -1,460,351,000 | -1,389,673,000 | -1,330,129,000 | -1,247,091,000 | -1,177,511,000 | -1,090,511,000 | -1,030,552,000 | -854,801,000 | -794,054,000 | -699,571,000 | -644,986,000 | -586,816,000 | -514,395,000 | -454,341,000 | -428,294,000 | -394,225,000 | -374,050,000 | -386,330,000 | -363,196,000 | -341,679,000 | -297,136,000 | -259,274,000 | -222,966,000 | -187,187,000 | -141,532,000 | -122,057,000 | -111,368,000 | -100,673,000 | -90,303,000 | -80,954,522 | |
total stockholders' equity | 27,375,000 | 32,610,000 | 41,592,000 | 29,224,000 | 24,581,000 | 9,342,000 | 13,853,000 | 62,300,000 | 26,116,000 | 76,456,000 | 137,150,000 | 174,631,000 | 213,891,000 | 247,618,000 | 317,962,000 | 370,260,000 | 396,364,000 | 394,757,000 | 467,562,000 | 519,356,000 | 566,379,000 | 635,928,000 | 142,541,000 | 165,924,000 | 197,097,000 | 119,331,000 | 99,875,000 | 56,998,000 | 30,617,000 | 68,120,000 | 100,710,000 | 133,288,000 | 167,762,000 | 145,412,000 | 149,752,000 | 94,609,000 | 104,078,000 | 113,614,000 | ||||||||||
total liabilities and stockholders' equity | 362,520,000 | 376,565,000 | 364,152,000 | 345,595,000 | 310,185,000 | 521,804,000 | 351,830,000 | 435,894,000 | 521,804,000 | 535,356,000 | 525,550,000 | 602,267,000 | 611,863,000 | 628,703,000 | 644,139,000 | 676,143,000 | 745,174,000 | 787,719,000 | 771,201,000 | 795,220,000 | 823,528,000 | 890,793,000 | 996,540,000 | 403,826,000 | 413,781,000 | 442,713,000 | 364,247,000 | 338,589,000 | 336,822,000 | 259,256,000 | 300,216,000 | 169,118,000 | 195,635,000 | 221,440,000 | 159,588,000 | 155,665,000 | 103,459,000 | |||||||||||
short-term deferred revenue | 2,681,000 | 695,000 | 3,738,000 | 1,265,000 | 5,047,000 | 10,440,000 | 20,906,000 | 15,692,000 | 11,869,000 | 18,253,000 | 15,214,000 | 18,034,000 | 23,529,000 | 34,886,000 | 39,830,000 | 32,142,000 | 40,316,000 | 49,584,000 | 56,980,000 | 70,099,000 | 78,613,000 | 78,592,000 | 84,910,000 | 121,031,000 | 142,346,000 | 84,108,000 | 81,968,000 | |||||||||||||||||||||
long-term operating lease liabilities | 671,000 | 2,123,000 | 3,547,000 | 4,937,000 | 6,299,000 | 7,636,000 | 8,947,000 | 10,227,000 | ||||||||||||||||||||||||||||||||||||||||
stockholders' equity | ||||||||||||||||||||||||||||||||||||||||||||||||
common stock: 0.00001 par value... | 2,000 | 2,000 | 2,000 | 2,000 | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | |||||||||||||||||||||||||||||||||||||
liabilities and stockholders' deficit | ||||||||||||||||||||||||||||||||||||||||||||||||
intangible asset | 9,011,000 | 18,021,000 | 27,032,000 | 36,042,000 | 45,053,000 | |||||||||||||||||||||||||||||||||||||||||||
long-term deferred revenue | ||||||||||||||||||||||||||||||||||||||||||||||||
stockholders' deficit: | ||||||||||||||||||||||||||||||||||||||||||||||||
total stockholders' deficit | -49,185,000 | -50,402,000 | -33,754,000 | -27,258,000 | ||||||||||||||||||||||||||||||||||||||||||||
total liabilities and stockholders' deficit | 220,670,000 | 207,142,000 | 220,196,000 | 225,477,000 | ||||||||||||||||||||||||||||||||||||||||||||
liability related to settlement royalties | 47,731,000 | |||||||||||||||||||||||||||||||||||||||||||||||
working capital fund liability | 40,203,000 | |||||||||||||||||||||||||||||||||||||||||||||||
deferred revenue, net of current portion | 43,296,000 | 43,296,000 | 43,296,000 | 43,296,000 | 43,296,000 | 43,296,000 | 43,296,000 | 65,356,000 | 21,474,000 | 27,965,000 | 16,598,000 | 19,299,000 | 25,345,000 | 33,660,000 | 34,542,000 | 42,799,000 | 33,120,000 | 43,887,000 | 55,558,000 | 56,887,000 | 55,709,000 | 81,424,000 | 80,890,000 | 91,641,000 | 97,957,000 | 84,701,000 | 95,531,000 | 92,315,000 | 115,321,000 | 40,000,000 | ||||||||||||||||||
refund liability to customer | 40,018,000 | 39,927,000 | 40,093,000 | 40,346,000 | 40,794,000 | 40,992,000 | ||||||||||||||||||||||||||||||||||||||||||
liability related to sale of future royalties | 53,498,000 | 54,013,000 | 56,061,000 | 57,059,000 | 57,484,000 | 58,236,000 | 56,743,000 | 55,095,000 | 53,079,000 | 51,137,000 | 49,094,000 | 46,925,000 | ||||||||||||||||||||||||||||||||||||
liabilities and stockholders' (deficit) equity | ||||||||||||||||||||||||||||||||||||||||||||||||
embedded debt derivative | 760,000 | |||||||||||||||||||||||||||||||||||||||||||||||
stockholders' (deficit) equity: | ||||||||||||||||||||||||||||||||||||||||||||||||
total stockholders' (deficit) equity | -30,584,000 | -39,422,000 | -14,352,000 | |||||||||||||||||||||||||||||||||||||||||||||
total liabilities and stockholders' (deficit) equity | 241,703,000 | 234,998,000 | 276,858,000 | |||||||||||||||||||||||||||||||||||||||||||||
revenues: | ||||||||||||||||||||||||||||||||||||||||||||||||
product revenue | 170,301,000 | 40,118,000 | ||||||||||||||||||||||||||||||||||||||||||||||
license, collaboration and other revenue | 24,322,000 | 1,928,000 | ||||||||||||||||||||||||||||||||||||||||||||||
total revenues | 194,623,000 | 42,046,000 | ||||||||||||||||||||||||||||||||||||||||||||||
cost of goods sold: | ||||||||||||||||||||||||||||||||||||||||||||||||
cost of product and other revenue | 38,107,000 | |||||||||||||||||||||||||||||||||||||||||||||||
amortization of intangible asset | 36,042,000 | 9,011,000 | ||||||||||||||||||||||||||||||||||||||||||||||
total cost of goods sold | 74,149,000 | 18,009,000 | ||||||||||||||||||||||||||||||||||||||||||||||
operating expenses: | ||||||||||||||||||||||||||||||||||||||||||||||||
research and development | 63,079,000 | 13,330,000 | ||||||||||||||||||||||||||||||||||||||||||||||
selling, general and administrative | 100,233,000 | 22,710,000 | ||||||||||||||||||||||||||||||||||||||||||||||
license | 3,237,000 | |||||||||||||||||||||||||||||||||||||||||||||||
restructuring | 181,000 | 169,000 | ||||||||||||||||||||||||||||||||||||||||||||||
total operating expenses | 166,730,000 | 37,073,000 | ||||||||||||||||||||||||||||||||||||||||||||||
income from operations | -46,256,000 | -13,036,000 | ||||||||||||||||||||||||||||||||||||||||||||||
other income: | ||||||||||||||||||||||||||||||||||||||||||||||||
interest expense | -6,032,000 | -1,410,000 | ||||||||||||||||||||||||||||||||||||||||||||||
other income | 887,000 | -43,000 | ||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | ||||||||||||||||||||||||||||||||||||||||||||||||
loss on termination of lease | -524,000 | |||||||||||||||||||||||||||||||||||||||||||||||
net income before income taxes | -51,925,000 | |||||||||||||||||||||||||||||||||||||||||||||||
net income | -51,925,000 | -14,489,000 | ||||||||||||||||||||||||||||||||||||||||||||||
comprehensive loss | -51,925,000 | -14,489,000 | ||||||||||||||||||||||||||||||||||||||||||||||
net income per share | ||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted | -280 | -80 | ||||||||||||||||||||||||||||||||||||||||||||||
weighted-average number of common shares outstanding: | ||||||||||||||||||||||||||||||||||||||||||||||||
revenues | ||||||||||||||||||||||||||||||||||||||||||||||||
cost of goods sold | ||||||||||||||||||||||||||||||||||||||||||||||||
product | 8,998,000 | |||||||||||||||||||||||||||||||||||||||||||||||
license expense | 864,000 | |||||||||||||||||||||||||||||||||||||||||||||||
weighted-average common shares outstanding: | ||||||||||||||||||||||||||||||||||||||||||||||||
condensed consolidated balance sheet | ||||||||||||||||||||||||||||||||||||||||||||||||
other non-current liabilities | 66,889,000 | 12,643,000 | 12,161,000 | 74,313,000 | 66,889,000 | 77,743,000 | 82,525,000 | 77,393,000 | 85,363,000 | 53,617,000 | 60,611,000 | 40,971,000 | 41,508,000 | 30,385,000 | 30,223,000 | 30,060,000 | 29,898,000 | 29,736,000 | 29,573,000 | 41,000 | 69,000 | 21,000 | 22,000 | 23,000 | 24,000 | 26,000 | 27,000 | 7,000 | 9,000 | 12,000 | ||||||||||||||||||
inventory | 20,604,000 | 21,762,000 | 40,039,000 | 36,272,000 | 39,422,000 | 38,195,000 | 33,688,000 | 37,898,000 | 44,806,000 | 61,017,000 | 88,242,000 | 104,603,000 | 111,854,000 | 116,349,000 | 115,987,000 | 122,137,000 | 115,206,000 | 114,245,000 | ||||||||||||||||||||||||||||||
operating lease assets | 27,958,000 | 29,158,000 | 30,337,000 | 31,494,000 | 32,631,000 | 33,852,000 | 23,192,000 | 24,442,000 | 25,670,000 | 26,876,000 | 25,721,000 | 26,884,000 | 28,026,000 | 29,038,000 | 30,141,000 | 31,224,000 | 32,399,000 | |||||||||||||||||||||||||||||||
other intangible assets | 63,074,000 | 72,084,000 | 81,095,000 | 90,106,000 | 99,116,000 | 108,127,000 | 117,138,000 | 126,148,000 | 135,159,000 | 144,170,000 | 151,378,000 | 157,484,000 | 282,112,000 | 291,212,000 | 300,312,000 | 309,413,000 | 318,513,000 | 328,153,000 | ||||||||||||||||||||||||||||||
other assets | 5,238,000 | 5,372,000 | 26,275,000 | 34,953,000 | 39,418,000 | 49,754,000 | 69,604,000 | 67,474,000 | 39,636,000 | 37,981,000 | 44,170,000 | 47,271,000 | 71,917,000 | 75,985,000 | 97,907,000 | 100,539,000 | 128,083,000 | 137,036,000 | 2,492,000 | 2,638,000 | 2,018,000 | 2,274,000 | 1,287,000 | 1,499,000 | 1,299,000 | 1,283,000 | 1,283,000 | 1,281,000 | 1,281,000 | 305,000 | 305,000 | 305,000 | 305,000 | 125,000 | 125,345 | 125,345 | ||||||||||||
operating lease liabilities, net of current portion | 27,418,000 | 28,961,000 | 30,683,000 | 31,733,000 | 32,581,000 | 33,703,000 | 20,257,000 | 21,735,000 | 23,185,000 | 24,621,000 | 23,494,000 | 24,862,000 | 26,207,000 | 27,528,000 | 28,811,000 | 30,069,000 | 31,304,000 | |||||||||||||||||||||||||||||||
derivative liability | 760,000 | 760,000 | 760,000 | 1,110,000 | 1,110,000 | 1,820,000 | 1,930,000 | 1,930,000 | 2,500,000 | 2,420,000 | 1,990,000 | 1,890,000 | 1,740,000 | 1,650,000 | ||||||||||||||||||||||||||||||||||
accumulated other comprehensive gain | 6,000 | 6,000 | 6,000 | 13,000 | ||||||||||||||||||||||||||||||||||||||||||||
current portion of refund liability to customer | 13,681,000 | 14,247,000 | 16,500,000 | |||||||||||||||||||||||||||||||||||||||||||||
refund liability to customer, net of current portion | 26,788,000 | 26,053,000 | 23,441,000 | |||||||||||||||||||||||||||||||||||||||||||||
accumulated other comprehensive loss | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | 9,000 | 6,000 | -9,000 | -36,000 | -261,000 | -409,000 | -459,000 | -550,000 | -181,000 | -254,000 | -179,000 | -7,000 | -27,000 | -7,000 | -27,000 | -8,000 | -56,000 | -52,000 | -8,216 | ||||||||||||||||||||||||
available for sale securities | 19,999,000 | 39,992,000 | 99,969,000 | 49,943,000 | 245,000 | 22,727,000 | 49,553,000 | 105,297,000 | 216,996,000 | 227,714,000 | 238,597,000 | 234,858,000 | 247,636,000 | 240,106,000 | 195,825,000 | 164,555,000 | 73,008,000 | 95,492,000 | 142,472,000 | 173,586,000 | 90,754,000 | 76,541,000 | 72,446,000 | 76,138,000 | 68,670,000 | |||||||||||||||||||||||
accrued expenses | 129,071,000 | 150,917,000 | 94,616,000 | 81,012,000 | 54,947,000 | 52,441,000 | 21,427,000 | 28,851,000 | 34,272,000 | 30,261,000 | 17,615,000 | 15,789,000 | 10,994,000 | 8,893,000 | 3,491,000 | 4,512,000 | 4,864,000 | 3,490,000 | 3,277,593 | 4,042,007 | ||||||||||||||||||||||||||||
deferred rent, net of current portion | 3,006,000 | 2,421,000 | 2,478,000 | 2,535,000 | 2,588,000 | 2,633,000 | 2,678,000 | 257,000 | ||||||||||||||||||||||||||||||||||||||||
deferred tax liabilities | 1,752,000 | 3,029,000 | 3,874,000 | 6,631,000 | ||||||||||||||||||||||||||||||||||||||||||||
debt | 15,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||
unbilled receivable | 281,000 | 33,823,000 | ||||||||||||||||||||||||||||||||||||||||||||||
short-term deferred rent | 194,000 | 182,000 | ||||||||||||||||||||||||||||||||||||||||||||||
deferred rent | 2,835,000 | 2,480,000 | 2,262,000 | 1,406,000 | ||||||||||||||||||||||||||||||||||||||||||||
deferred offering costs | 55,000 | |||||||||||||||||||||||||||||||||||||||||||||||
treasury stock | -162,000 | -162,000 | -162,000 | -161,000 | -162,000 | -79,000 | -21,362 | |||||||||||||||||||||||||||||||||||||||||
deferred revenue | 40,000,000 | 40,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||
other liabilities | 10,000 | 10,000 | 9,000 | 32,000 | 34,000 | 29,532 | 30,434 | |||||||||||||||||||||||||||||||||||||||||
liabilities, redeemable convertible preferred stock and stockholders' equity | ||||||||||||||||||||||||||||||||||||||||||||||||
redeemable convertible preferred stock; 0.00001 par value... | ||||||||||||||||||||||||||||||||||||||||||||||||
series a redeemable convertible preferred stock; 0 and 734,538 shares issued and outstanding at december 31, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series b redeemable convertible preferred stock; 0 and 1,287,525 shares issued and outstanding at december 31, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series c redeemable convertible preferred stock; 0 and 3,302,885 shares issued and outstanding at december 31, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
total redeemable convertible preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||
total liabilities, redeemable convertible preferred stock and stockholders' equity | 110,995,000 | 120,170,000 | ||||||||||||||||||||||||||||||||||||||||||||||
series a redeemable convertible preferred stock; 0 and 734,538 shares issued and outstanding at september 30, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series b redeemable convertible preferred stock; 0 and 1,287,525 shares issued and outstanding at september 30, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series c redeemable convertible preferred stock; 0 and 3,302,885 shares issued and outstanding at september 30, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
investments | 28,851,842 | 5,831,843 | ||||||||||||||||||||||||||||||||||||||||||||||
liabilities, redeemable convertible preferred stock and stockholders’ equity | ||||||||||||||||||||||||||||||||||||||||||||||||
current portion of capital lease obligation | 3,939 | 3,911 | ||||||||||||||||||||||||||||||||||||||||||||||
capital lease obligation, net of current portion | 6,369 | 7,364 | ||||||||||||||||||||||||||||||||||||||||||||||
series a redeemable convertible preferred stock; 0 and 734,538 shares issued and outstanding at june 30, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series b redeemable convertible preferred stock; 0 and 1,287,525 shares issued and outstanding at june 30, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series c redeemable convertible preferred stock; 0 and 3,302,885 shares issued and outstanding at june 30, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
stockholders’ equity | ||||||||||||||||||||||||||||||||||||||||||||||||
common stock; 0.00001 par value... | 202 | 202 | ||||||||||||||||||||||||||||||||||||||||||||||
total stockholders’ equity | 121,551,966 | 127,867,391 | ||||||||||||||||||||||||||||||||||||||||||||||
total liabilities, redeemable convertible preferred stock and stockholders’ equity | 126,357,583 | 134,028,409 | ||||||||||||||||||||||||||||||||||||||||||||||
equipment | 164,204 | |||||||||||||||||||||||||||||||||||||||||||||||
series a redeemable convertible preferred stock; 0 and 734,538 shares issued and outstanding at march 31, 2014 and december 31, 2013; (aggregate liquidation preference of 39,367,094 at december 31, 2013 | ||||||||||||||||||||||||||||||||||||||||||||||||
series b redeemable convertible preferred stock; 0 and 1,287,525 shares issued and outstanding at march 31, 2014 and december 31, 2013; | ||||||||||||||||||||||||||||||||||||||||||||||||
series c redeemable convertible preferred stock; 0 and 3,302,885 shares issued and outstanding at march 31, 2014 and december 31, 2013; (aggregate liquidation preference of 97,202,997 at december 31, 2013 | ||||||||||||||||||||||||||||||||||||||||||||||||
deficit accumulated during the development stage | -73,336,195 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
operating activities: | ||||||||||||||||||||||||||||||||||||||||||||||||
net income | -9,054,000 | 540,000 | 247,000 | 6,112,000 | ||||||||||||||||||||||||||||||||||||||||||||
adjustments to reconcile net income to net cash from operating activities: | ||||||||||||||||||||||||||||||||||||||||||||||||
depreciation | 328,000 | 321,000 | 318,000 | 316,000 | 314,000 | 335,000 | 363,000 | 400,000 | 364,000 | |||||||||||||||||||||||||||||||||||||||
bad debt expense | 199,000 | 94,000 | 426,000 | 257,000 | 702,000 | |||||||||||||||||||||||||||||||||||||||||||
change in fair value of warrant liability | -456,000 | -2,262,000 | -1,464,000 | 6,980,000 | -155,000 | 1,675,000 | 856,000 | -2,330,000 | 129,000 | |||||||||||||||||||||||||||||||||||||||
non-cash royalty revenue related to sale of future royalties | -341,000 | -443,000 | -462,000 | -494,000 | -369,000 | -505,000 | -525,000 | -474,000 | -391,000 | -487,000 | -511,000 | -425,000 | -582,000 | -431,000 | -435,000 | -329,000 | -396,000 | -309,000 | -96,000 | -20,000 | ||||||||||||||||||||||||||||
non-cash interest expense | 4,577,000 | 4,752,000 | 4,619,000 | 6,184,000 | 6,253,000 | 5,594,000 | 7,246,000 | -97,000 | 326,000 | 335,000 | 481,000 | 502,000 | 654,000 | 551,000 | 670,000 | 246,000 | 313,000 | 313,000 | 310,000 | 229,000 | 279,000 | 383,000 | 435,000 | 437,000 | 278,000 | 169,000 | 170,000 | 169,000 | ||||||||||||||||||||
non-cash operating lease expense | 1,198,000 | 1,174,000 | 1,150,000 | 1,127,000 | 1,104,000 | 1,060,000 | 1,039,000 | 1,017,000 | -266,000 | -377,000 | -578,000 | -599,000 | -620,000 | -641,000 | -557,000 | -427,000 | -450,000 | -471,000 | -494,000 | -377,000 | -496,000 | -517,000 | -647,000 | -556,000 | -576,000 | -483,000 | -614,000 | |||||||||||||||||||||
write-down of inventory | 3,216,000 | 1,860,000 | 530,000 | -48,000 | 163,000 | 1,805,000 | 1,342,000 | 471,000 | 590,000 | 715,000 | 277,000 | 335,000 | 20,240,000 | 2,572,000 | 2,086,000 | 5,344,000 | 8,492,000 | 1,701,000 | 350,000 | 5,075,000 | 1,464,000 | 8,519,000 | 9,950,000 | 139,000 | ||||||||||||||||||||||||
gain on the sale of property and equipment | 0 | 0 | 0 | -172,000 | ||||||||||||||||||||||||||||||||||||||||||||
stock-based compensation expense | 3,668,000 | 3,199,000 | 3,221,000 | 2,676,000 | 2,187,000 | 1,697,000 | 1,646,000 | 2,072,000 | 2,360,000 | 1,514,000 | 1,824,000 | 1,251,000 | 1,163,000 | 1,095,000 | 1,128,000 | 885,000 | 1,236,192 | 1,443,944 | 2,444,864 | |||||||||||||||||||||||||||||
changes in operating assets and liabilities: | ||||||||||||||||||||||||||||||||||||||||||||||||
accounts receivable | -15,704,000 | 19,098,000 | 6,160,000 | -11,528,000 | -27,872,000 | -3,074,000 | -2,405,000 | -3,145,000 | 12,670,000 | -16,698,000 | -3,020,000 | -687,000 | 21,399,000 | -16,086,000 | 58,775,000 | -17,287,000 | -13,707,000 | -1,185,000 | -14,685,000 | 228,000 | -8,380,000 | -2,387,000 | 14,649,000 | 65,757,000 | -66,008,000 | -9,210,000 | -766,000 | 19,547,000 | -31,769,000 | -144,000 | -556,000 | 35,720,000 | -1,636,000 | -26,000 | 9,000 | 56,614 | 5,442 | 15,944 | ||||||||||
inventory | -2,540,000 | -17,418,000 | 6,899,000 | -7,653,000 | -4,953,000 | -545,000 | -14,926,000 | -4,434,000 | -1,590,000 | 3,481,000 | 7,347,000 | 18,388,000 | 246,000 | 6,406,000 | -5,247,000 | 9,435,000 | 428,000 | -16,517,000 | -19,193,000 | -252,000 | 12,095,000 | 2,483,000 | -8,163,000 | -577,000 | -11,377,000 | -1,124,000 | -16,064,000 | |||||||||||||||||||||
prepaid expenses and other current assets | 170,000 | 1,560,000 | 2,501,000 | 1,306,000 | 2,212,000 | 2,088,000 | 5,523,000 | -130,000 | 1,412,000 | 1,796,000 | 2,359,000 | 306,000 | 7,378,000 | -8,750,000 | 8,570,000 | -8,458,000 | 9,019,000 | 6,362,000 | -28,321,000 | 1,033,000 | 2,268,000 | -5,840,000 | 998,000 | -1,379,000 | -1,898,000 | 1,126,000 | 20,752,000 | -12,654,000 | 1,317,000 | -631,000 | -1,532,000 | 2,682,000 | -1,496,000 | -2,396,000 | 7,222,000 | -7,926,000 | -1,093,000 | 1,691,000 | 48,000 | -1,369,000 | 58,000 | 800,000 | 165,000 | -775,000 | -85,000 | 261,605 | -230,071 | -719,534 |
other long-term assets | -749,000 | -2,763,000 | 38,000 | 49,000 | 54,000 | -3,000 | 173,000 | 1,065,000 | -613,000 | 6,814,000 | -2,299,000 | -3,064,000 | -2,812,000 | -20,440,000 | 5,470,000 | 6,050,000 | 3,297,000 | 946,000 | 579,000 | 2,788,000 | 1,361,000 | 3,739,000 | -6,575,000 | 11,000 | 46,000 | 1,772,000 | -226,000 | 2,652,000 | 719,000 | 836,000 | 146,000 | -987,000 | 75,000 | -78,000 | -1,000 | |||||||||||||
accounts payable | -7,792,000 | 10,419,000 | -8,828,000 | 3,725,000 | -2,234,000 | 2,394,000 | -3,032,000 | 6,775,000 | -7,501,000 | 4,503,000 | 2,311,000 | -3,045,000 | -9,013,000 | 18,921,000 | -8,613,000 | -1,449,000 | -7,358,000 | 3,198,000 | -13,813,000 | 3,792,000 | -4,912,000 | 650,000 | 8,007,000 | -25,449,000 | 20,470,000 | -25,066,000 | 46,066,000 | 1,118,000 | -20,746,000 | 8,031,000 | 7,889,000 | -13,085,000 | 10,882,000 | -1,707,000 | -1,507,000 | -4,871,000 | 13,044,000 | -6,470,000 | 3,366,000 | 2,728,000 | 102,000 | |||||||
accrued expense and other current liabilities | 2,035,000 | 13,928,000 | 15,824,000 | 16,007,000 | 2,771,000 | 4,875,000 | -3,126,000 | 519,000 | -15,045,000 | 3,714,000 | 5,647,000 | |||||||||||||||||||||||||||||||||||||
operating lease liabilities | -1,422,000 | -1,388,000 | -1,364,000 | -1,337,000 | -1,310,000 | -1,253,000 | -1,228,000 | -731,000 | 94,000 | 383,000 | 651,000 | 540,000 | 566,000 | 589,000 | 616,000 | 14,225,000 | 369,000 | 397,000 | 407,000 | 379,000 | 163,000 | 424,000 | 445,000 | 954,000 | 505,000 | 523,000 | 549,000 | |||||||||||||||||||||
deferred revenue | 1,815,000 | -1,200,000 | -1,651,000 | 4,291,000 | 1,241,000 | 695,000 | 0 | 0 | 0 | -3,738,000 | 2,473,000 | -3,782,000 | -27,453,000 | 33,416,000 | -1,277,000 | 15,190,000 | -9,085,000 | -3,007,000 | -11,135,000 | -6,377,000 | -19,614,000 | 4,735,000 | -3,079,000 | -19,845,000 | -10,597,000 | -6,218,000 | -38,834,000 | -7,980,000 | -10,730,000 | -9,391,000 | -22,865,000 | -32,145,000 | 61,454,000 | -20,866,000 | 157,289,000 | 0 | 0 | 40,000,000 | ||||||||||
other long-term liabilities | -355,000 | -365,000 | -352,000 | 240,000 | 365,000 | 264,000 | -2,990,000 | -1,878,000 | -1,600,000 | 1,536,000 | -7,708,000 | |||||||||||||||||||||||||||||||||||||
net cash from operating activities | -21,207,000 | 31,129,000 | 28,105,000 | 22,345,000 | -13,587,000 | -4,466,000 | -6,695,000 | -10,066,000 | -19,432,000 | -2,308,000 | -7,167,000 | 3,629,000 | -17,538,000 | -54,679,000 | 33,805,000 | -30,660,000 | -21,620,000 | -62,808,000 | -56,270,000 | -63,141,000 | -70,746,000 | -30,782,000 | -27,237,000 | 37,220,000 | -89,589,000 | -92,135,000 | 10,989,000 | -38,366,000 | -137,929,000 | -73,699,000 | -12,461,000 | 8,996,000 | -20,330,000 | -16,378,000 | -54,617,000 | 24,364,000 | -9,528,000 | 95,670,000 | -28,243,000 | -26,955,000 | 17,434,000 | -9,031,000 | -12,117,000 | -8,347,000 | -9,203,000 | -5,602,934 | -6,669,396 | -6,007,670 |
capital expenditures | -62,000 | 0 | -77,000 | -126,000 | -18,000 | 0 | -2,000 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -141,956 |
free cash flows | -21,269,000 | 31,129,000 | 28,028,000 | 22,219,000 | -13,605,000 | -4,466,000 | -6,697,000 | -10,066,000 | -19,432,000 | -2,308,000 | -7,167,000 | 3,629,000 | -17,538,000 | -54,679,000 | 33,805,000 | -30,660,000 | -21,620,000 | -62,808,000 | -56,270,000 | -63,141,000 | -70,746,000 | -30,782,000 | -27,237,000 | 37,220,000 | -89,589,000 | -92,135,000 | 10,989,000 | -38,366,000 | -137,929,000 | -73,699,000 | -12,461,000 | 8,996,000 | -20,330,000 | -16,378,000 | -54,617,000 | 24,364,000 | -9,528,000 | 95,670,000 | -28,243,000 | -26,955,000 | 17,434,000 | -9,031,000 | -12,117,000 | -8,347,000 | -9,203,000 | -5,602,934 | -6,669,396 | -6,149,626 |
investing activities: | ||||||||||||||||||||||||||||||||||||||||||||||||
purchases of equipment | -62,000 | -77,000 | -126,000 | -18,000 | -2,000 | |||||||||||||||||||||||||||||||||||||||||||
proceeds from the sale of property and equipment | 0 | 0 | 0 | 172,000 | ||||||||||||||||||||||||||||||||||||||||||||
net cash from investing activities | -62,000 | -7,877,000 | -77,000 | -126,000 | 154,000 | -2,000 | -2,000 | 0 | 0 | 0 | -114,000 | 0 | 0 | 20,000,000 | 19,941,000 | 59,683,000 | -49,937,000 | -49,995,000 | 245,000 | 22,280,000 | 24,390,000 | 54,033,000 | 110,473,000 | 16,717,000 | 11,011,000 | -3,568,000 | 12,434,000 | -8,308,000 | -44,959,000 | -31,690,000 | -92,303,000 | 22,306,000 | 45,567,000 | 29,787,000 | -84,955,000 | -14,455,000 | -4,276,000 | 3,405,000 | -7,637,000 | -39,998,296 | -23,074,748 | 5,358,044 | ||||||
financing activities: | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from the issuance of debt | 0 | 0 | 0 | 10,000,000 | 0 | 0 | 8,000,000 | 37,000,000 | ||||||||||||||||||||||||||||||||||||||||
payments of issuance costs related to blackrock credit agreement | 0 | 0 | 0 | -63,000 | 0 | -522,000 | 0 | -750,000 | ||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of common stock, net of issuance costs | 0 | 1,542,000 | 64,907,000 | 1,662,000 | 0 | 18,740,000 | 35,000 | |||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of stock under employee stock purchase plan | 131,000 | 152,000 | 0 | 78,000 | 83,000 | 0 | 70,000 | |||||||||||||||||||||||||||||||||||||||||
proceeds from the exercise of stock options | 20,000 | 961,000 | 178,000 | 482,000 | 0 | 14,000 | 141,000 | 0 | 0 | 0 | 405,000 | 409,000 | 412,000 | 0 | 0 | 195,000 | 365,000 | 92,000 | 58,000 | 314,000 | 183,000 | 204,000 | 930,000 | 110,000 | 68,000 | -1,000 | 5,000 | 101,000 | 19,000 | -3,000 | ||||||||||||||||||
repayment of wcf liability | -492,000 | |||||||||||||||||||||||||||||||||||||||||||||||
repayment of liability related to settlement royalties | -585,000 | |||||||||||||||||||||||||||||||||||||||||||||||
repayment of term debt | 0 | 0 | 0 | -462,000 | 1,000 | 0 | -374,000 | -36,726,000 | ||||||||||||||||||||||||||||||||||||||||
net cash from financing activities | -926,000 | -4,848,000 | 1,113,000 | 1,720,000 | 74,942,000 | 22,325,000 | 1,223,000 | 7,640,000 | 18,475,000 | -1,290,000 | 50,000 | -8,000,000 | -15,966,000 | -1,000 | -32,937,000 | -9,000 | 47,545,000 | 5,403,000 | 16,482,000 | 37,369,000 | 74,477,000 | 30,511,000 | 1,054,000 | 142,807,000 | 57,348,000 | 94,418,000 | 195,000 | 8,804,000 | -14,447,000 | 85,000 | 354,000 | 212,000 | 95,911,000 | 5,243,000 | 63,785,000 | 45,466,000 | 1,746,000 | 3,529,000 | 2,329,000 | -94,000 | 61,182,000 | 13,950,000 | 64,754,000 | 49,000 | -48,000 | -124,644 | -1,181,211 | 105,753,855 |
increase in cash, cash equivalents and restricted cash | -22,195,000 | 18,404,000 | 29,141,000 | 23,939,000 | 61,509,000 | |||||||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash — beginning of period | 186,543,000 | 0 | 0 | 53,550,000 | 0 | 0 | 44,579,000 | 0 | ||||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash — end of period | 164,348,000 | 29,141,000 | 23,939,000 | 115,059,000 | -5,474,000 | -2,455,000 | 43,622,000 | -7,117,000 | ||||||||||||||||||||||||||||||||||||||||
non-cash financing activities | ||||||||||||||||||||||||||||||||||||||||||||||||
issuance of warrants in connection with blackrock credit agreement | 0 | 0 | 0 | 2,199,000 | 0 | 0 | 0 | 4,846,000 | ||||||||||||||||||||||||||||||||||||||||
purchase of ipr&d asset included in accrued expenses and other current liabilities | 5,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||
net loss | -22,804,000 | -20,039,000 | -8,582,000 | -17,985,000 | 614,000 | -14,489,000 | -11,833,000 | -26,217,000 | -7,552,000 | -51,865,000 | 29,276,000 | -62,421,000 | -70,678,000 | -59,544,000 | -83,038,000 | -69,580,000 | -87,000,000 | -59,959,000 | -175,751,000 | -60,747,000 | -94,483,000 | -54,585,000 | -58,170,000 | -72,421,000 | -60,054,000 | -26,047,000 | -34,069,000 | -23,418,000 | 12,280,000 | -23,134,000 | -21,517,000 | -44,543,000 | -37,862,000 | -36,308,000 | -35,779,000 | -25,798,000 | -19,475,000 | -10,689,000 | -10,695,000 | -10,370,000 | -9,348,562 | -7,618,328 | -9,697,110 | |||||
adjustments to reconcile net loss to net cash from operating activities: | ||||||||||||||||||||||||||||||||||||||||||||||||
amortization of intangible asset | 9,010,000 | 9,011,000 | 9,010,000 | 9,011,000 | 9,010,000 | 9,011,000 | ||||||||||||||||||||||||||||||||||||||||||
non-cash research and development expense | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
non-cash loss on extinguishment of debt | 0 | 0 | 294,000 | 0 | ||||||||||||||||||||||||||||||||||||||||||||
non-cash write-off on termination of lease | ||||||||||||||||||||||||||||||||||||||||||||||||
charge for purchase of ipr&d asset | ||||||||||||||||||||||||||||||||||||||||||||||||
change in excess inventory purchase commitments | 0 | -80,040,000 | 13,195,000 | 0 | -773,000 | 18,015,000 | -5,962,000 | 30,283,000 | -8,945,000 | 14,810,000 | -650,000 | |||||||||||||||||||||||||||||||||||||
change in fair value of embedded debt derivative | ||||||||||||||||||||||||||||||||||||||||||||||||
purchase of equipment | 0 | 0 | -114,000 | 0 | 0 | -59,000 | -2,529,000 | -1,978,000 | -1,928,000 | -830,000 | -307,000 | -173,000 | -296,000 | -450,000 | -597,000 | -148,000 | -427,000 | -48,000 | -1,256,000 | -1,249,000 | -109,000 | -115,000 | -27,000 | -200,000 | -21,000 | |||||||||||||||||||||||
purchase of ipr&d asset, including transaction costs | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from the issuance of common stock, net of issuance costs | -1,000 | 20,000 | -76,000 | 7,178,000 | 5,403,000 | 16,103,000 | 37,369,000 | 29,327,000 | 10,536,000 | 0 | 142,398,000 | 56,485,000 | 16,750,000 | 0 | -1,000 | 38,000 | -96,000 | 95,511,000 | 5,039,000 | 62,629,000 | 45,357,000 | 1,555,000 | 3,531,000 | 2,336,000 | -297,000 | 61,166,000 | 13,955,000 | |||||||||||||||||||||
proceeds from the sale of stock under employee stock purchase plan | 34,000 | 0 | 43,000 | 0 | 367,000 | 0 | 379,000 | 0 | 367,000 | 0 | 649,000 | 0 | 451,000 | 0 | 195,000 | 0 | 188,000 | 0 | 265,000 | -1,000 | 218,000 | 1,000 | 227,000 | 0 | 125,000 | 0 | 1,000 | |||||||||||||||||||||
proceeds from the exercise of common stock options | ||||||||||||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at beginning of the period | ||||||||||||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at end of the period | ||||||||||||||||||||||||||||||||||||||||||||||||
supplemental cash flow information | ||||||||||||||||||||||||||||||||||||||||||||||||
cashless exercise of warrants in connection with blackrock credit agreement | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
cash paid for interest | ||||||||||||||||||||||||||||||||||||||||||||||||
unpaid issuance costs related to blackrock credit agreement | 0 | 522,000 | ||||||||||||||||||||||||||||||||||||||||||||||
amortization of right-of-use assets | ||||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | ||||||||||||||||||||||||||||||||||||||||||||||||
change in firm purchase commitments | ||||||||||||||||||||||||||||||||||||||||||||||||
inventories | ||||||||||||||||||||||||||||||||||||||||||||||||
lease liabilities | ||||||||||||||||||||||||||||||||||||||||||||||||
purchase of property and equipment | ||||||||||||||||||||||||||||||||||||||||||||||||
supplemental disclosure of cash flow information: | ||||||||||||||||||||||||||||||||||||||||||||||||
non-cash write-off from termination of lease | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
decrease in cash, cash equivalents and restricted cash | -5,474,000 | -2,455,000 | -957,000 | -3,598,000 | -7,117,000 | |||||||||||||||||||||||||||||||||||||||||||
depreciation expense | 32,000 | 35,000 | 31,000 | 19,000 | 16,000 | 12,908 | 11,974 | 8,118 | ||||||||||||||||||||||||||||||||||||||||
interest expense related to sale of future royalties | ||||||||||||||||||||||||||||||||||||||||||||||||
accretion of interest expense and amortization of refund liability | ||||||||||||||||||||||||||||||||||||||||||||||||
royalty revenue from mtpc | ||||||||||||||||||||||||||||||||||||||||||||||||
collaboration revenue in connection with the termination of the otsuka agreement | ||||||||||||||||||||||||||||||||||||||||||||||||
r&d expense in connection with the termination of the otsuka agreement | ||||||||||||||||||||||||||||||||||||||||||||||||
write-off on termination of boston lease | ||||||||||||||||||||||||||||||||||||||||||||||||
provision of inventories | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from refund liability to customer | ||||||||||||||||||||||||||||||||||||||||||||||||
principal payments on debt | ||||||||||||||||||||||||||||||||||||||||||||||||
non-cash interest expense related to sale of future royalties | -170,000 | 1,924,000 | 2,083,000 | 2,345,000 | 2,338,000 | 2,352,000 | 2,265,000 | 2,162,000 | ||||||||||||||||||||||||||||||||||||||||
non-cash collaboration revenue | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||
proceeds from refund liabilities to customers | 0 | 0 | 0 | 40,000,000 | ||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuances of stock under employee stock purchase plan | 50,000 | |||||||||||||||||||||||||||||||||||||||||||||||
repayments of term debt | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
depreciation and amortization | 397,000 | 398,000 | 408,000 | 413,000 | 416,000 | 417,000 | 442,000 | 473,000 | 499,000 | 513,000 | 516,000 | 514,000 | 520,000 | 525,000 | 586,000 | 633,000 | 587,000 | 439,000 | 261,000 | 225,000 | 214,000 | 199,000 | 197,000 | 167,000 | 118,000 | 135,000 | 124,000 | 94,000 | ||||||||||||||||||||
amortization of intangibles | 9,011,000 | 9,011,000 | 9,011,000 | 9,010,000 | 9,011,000 | 9,011,000 | 9,011,000 | 9,010,000 | 9,011,000 | 7,208,000 | 6,106,000 | 9,101,000 | 9,100,000 | 9,101,000 | 9,100,000 | 9,100,000 | ||||||||||||||||||||||||||||||||
non-cash r&d expense | 782,000 | |||||||||||||||||||||||||||||||||||||||||||||||
stock-based compensation | 2,489,000 | 3,041,000 | 3,355,000 | 6,917,000 | 4,536,000 | 4,636,000 | 5,593,000 | 6,514,000 | 5,992,000 | 6,088,000 | 6,592,000 | 6,864,000 | 4,916,000 | 4,934,000 | 2,613,000 | 2,284,000 | 2,094,000 | 12,062,000 | 2,253,000 | 2,493,000 | 2,232,000 | 1,724,000 | 1,628,000 | |||||||||||||||||||||||||
change in fair value of derivative liability | 0 | -350,000 | 0 | -710,000 | -110,000 | 0 | -570,000 | 80,000 | -54,000 | 100,000 | 150,000 | 90,000 | ||||||||||||||||||||||||||||||||||||
accrued expense | -25,047,000 | -15,863,000 | -3,739,000 | -23,051,000 | 4,426,000 | -39,779,000 | 30,805,000 | -10,829,000 | -4,877,000 | 12,428,000 | -19,683,000 | 17,820,000 | -4,209,000 | 1,825,000 | -1,050,000 | -10,626,000 | -17,500,000 | 13,364,000 | 13,571,000 | 26,148,000 | 2,399,000 | 30,808,000 | -7,287,000 | -5,545,000 | 3,998,000 | 12,686,000 | 1,655,000 | |||||||||||||||||||||
other non-current liabilities | 16,900,000 | -5,790,000 | -5,839,000 | -3,191,000 | ||||||||||||||||||||||||||||||||||||||||||||
payments on debt | -16,000,000 | 0 | 0 | 0 | 0 | -15,000,000 | ||||||||||||||||||||||||||||||||||||||||||
increase in cash, cash equivalents, and restricted cash | -33,504,000 | -30,669,000 | 25,811,000 | -57,405,000 | -39,788,000 | -5,772,000 | 23,672,000 | 59,412,000 | -76,120,000 | 130,032,000 | -31,996,000 | 24,563,000 | 35,574,000 | 24,471,000 | -41,903,000 | -56,897,000 | -1,096,000 | 5,640,000 | 88,015,000 | |||||||||||||||||||||||||||||
cash, cash equivalents, and restricted cash at beginning of the period | 93,169,000 | 0 | 0 | 0 | 151,839,000 | 0 | 0 | 0 | 231,132,000 | 0 | 0 | 0 | 149,804,000 | 0 | 0 | 0 | 107,099,000 | 0 | 0 | 0 | 71,437,000 | |||||||||||||||||||||||||||
cash, cash equivalents, and restricted cash at end of the period | 59,665,000 | -54,680,000 | 868,000 | -30,669,000 | 177,650,000 | -57,405,000 | -39,788,000 | -5,772,000 | 254,804,000 | 59,412,000 | -76,120,000 | 130,032,000 | 117,808,000 | 24,563,000 | 35,574,000 | 24,471,000 | 65,196,000 | -56,897,000 | -1,096,000 | 5,640,000 | 159,452,000 | |||||||||||||||||||||||||||
intangible asset impairment charge | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||
amortization of premium/discount on investments | 0 | 0 | -4,000 | -11,000 | -16,000 | -29,000 | -24,000 | -110,000 | -208,000 | -477,000 | -534,000 | -385,000 | -253,000 | -60,000 | 67,000 | 154,000 | 198,000 | 191,000 | 95,000 | 112,000 | 143,000 | 144,000 | 147,000 | 136,000 | 135,000 | 144,000 | 99,341 | |||||||||||||||||||||
fair value step-up of inventory sold or written off | 0 | 0 | 0 | 21,575,000 | 28,718,000 | 8,406,000 | ||||||||||||||||||||||||||||||||||||||||||
operating lease assets | ||||||||||||||||||||||||||||||||||||||||||||||||
purchase of available for sale securities | 0 | -49,982,000 | -51,778,000 | -50,972,000 | -72,867,000 | -48,599,000 | -61,170,000 | -116,366,000 | -14,871,000 | -13,454,000 | ||||||||||||||||||||||||||||||||||||||
proceeds from the maturities of available for sale securities | 0 | 0 | 20,000,000 | 20,000,000 | 60,000,000 | 0 | 0 | 245,000 | 22,500,000 | 26,919,000 | 25,000,000 | 78,691,000 | 63,178,000 | 57,288,000 | 66,473,000 | 56,330,000 | 52,130,000 | 43,750,000 | 29,628,000 | 24,490,000 | 37,225,000 | 60,277,000 | ||||||||||||||||||||||||||
proceeds from sale of future royalties | 0 | 0 | 0 | 44,783,000 | ||||||||||||||||||||||||||||||||||||||||||||
unpaid offering costs | -55,000 | -11,000 | -103,000 | 171,000 | 25,000 | 0 | -15,000 | 90,000 | ||||||||||||||||||||||||||||||||||||||||
cash paid for: | ||||||||||||||||||||||||||||||||||||||||||||||||
interest | ||||||||||||||||||||||||||||||||||||||||||||||||
(decrease) in cash, cash equivalents, and restricted cash | ||||||||||||||||||||||||||||||||||||||||||||||||
write-off of property and equipment | ||||||||||||||||||||||||||||||||||||||||||||||||
deferred income taxes | -1,752,000 | -1,277,000 | -845,000 | -2,757,000 | ||||||||||||||||||||||||||||||||||||||||||||
proceeds from sales of available for sale securities | 0 | 0 | 31,011,000 | 33,710,000 | 0 | 5,002,000 | 2,999,000 | 4,999,000 | ||||||||||||||||||||||||||||||||||||||||
retirement of treasury stock | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||
non-cash merger expense | ||||||||||||||||||||||||||||||||||||||||||||||||
deferred rent | 549,000 | -45,000 | -45,000 | -41,000 | -33,000 | -33,000 | 25,000 | 355,000 | 218,000 | 856,000 | 30,434 | |||||||||||||||||||||||||||||||||||||
acquisition of business, net of acquired cash and restricted cash | ||||||||||||||||||||||||||||||||||||||||||||||||
payments on capital lease obligations | -6,000 | -7,000 | -5,000 | -1,000 | -1,000 | -1,000 | -1,000 | -2,000 | -1,000 | -13,000 | -3,000 | -3,000 | -2,000 | -2,000 | -1,000 | 0 | -1,392 | -967 | -641 | |||||||||||||||||||||||||||||
fair value of shares and equity awards issued in acquisition | ||||||||||||||||||||||||||||||||||||||||||||||||
fair value write-up of inventory sold | 11,180,000 | 18,840,000 | 18,017,000 | 19,001,000 | 14,586,000 | |||||||||||||||||||||||||||||||||||||||||||
amortization of intangible assets | ||||||||||||||||||||||||||||||||||||||||||||||||
fair value of warrants issued for license | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||
write-down of inventory to net realizable value | 2,945,000 | 1,359,000 | 1,664,000 | |||||||||||||||||||||||||||||||||||||||||||||
unpaid follow-on offering costs | 95,000 | 127,000 | 10,000 | -53,000 | -66,000 | 111,000 | 20,000 | |||||||||||||||||||||||||||||||||||||||||
loss on disposal of property and equipment | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
increase in cash and cash equivalents | -19,443,000 | -9,536,000 | 48,361,000 | -4,893,000 | -16,888,000 | -45,725,874 | -30,925,355 | 105,104,229 | ||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents at beginning of the period | 0 | 0 | 0 | 187,335,000 | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents at end of the period | -19,443,000 | -35,791,000 | 38,140,000 | 87,250,000 | 121,505,000 | 19,653,000 | ||||||||||||||||||||||||||||||||||||||||||
assets acquired under capital lease | 0 | 0 | 12,000 | |||||||||||||||||||||||||||||||||||||||||||||
stock-based compensation - equity awards | 2,152,000 | 2,506,000 | 2,016,000 | |||||||||||||||||||||||||||||||||||||||||||||
unbilled receivable | -281,000 | 0 | 33,823,000 | |||||||||||||||||||||||||||||||||||||||||||||
purchases of available for sale securities | -100,160,000 | -29,097,000 | -29,454,000 | -5,980,000 | -13,211,000 | |||||||||||||||||||||||||||||||||||||||||||
decrease in cash and cash equivalents | 38,140,000 | -100,085,000 | 19,653,000 | 2,738,000 | -6,339,000 | |||||||||||||||||||||||||||||||||||||||||||
stock-based compensation - warrants | 3,413,000 | |||||||||||||||||||||||||||||||||||||||||||||||
repurchase of treasury stock | -83,000 | -57,638 | ||||||||||||||||||||||||||||||||||||||||||||||
payments received on promissory notes issued in exchange for shares of common stock | ||||||||||||||||||||||||||||||||||||||||||||||||
conversion of series a, series b and series c preferred stock into common stock | ||||||||||||||||||||||||||||||||||||||||||||||||
accretion of preferred stock to redemption value | 0 | -555 | ||||||||||||||||||||||||||||||||||||||||||||||
accrued expenses | 1,457,000 | |||||||||||||||||||||||||||||||||||||||||||||||
other liabilities | 188,000 | 2,000 | 3,000 | -30,000 | -1,000 | -532 | ||||||||||||||||||||||||||||||||||||||||||
proceeds from maturities of available for sale securities | 15,314,000 | 14,757,000 | 25,205,000 | 9,585,000 | 5,595,000 | |||||||||||||||||||||||||||||||||||||||||||
proceeds from sale of stock under employee stock purchase plan | ||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents at beginning of period | 49,778,000 | 0 | 0 | 32,780,000 | 0 | -228 | 0 | 21,215,228 | ||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents at end of period | 43,439,000 | -9,536,000 | 48,361,000 | 27,887,000 | -16,888,000 | -45,726,102 | -30,925,355 | 126,319,457 | ||||||||||||||||||||||||||||||||||||||||
non-cash financing activities: | ||||||||||||||||||||||||||||||||||||||||||||||||
accounts payable and accrued expenses | 8,263,000 | -2,884,000 | 1,897,000 | 378,000 | 2,079,500 | -306,114 | 1,909,614 | |||||||||||||||||||||||||||||||||||||||||
proceeds from employee stock purchase plan | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
unpaid initial public offering issuance costs | 14,878,650 | -1,047,418 | 1,168,768 | |||||||||||||||||||||||||||||||||||||||||||||
proceeds from the issuance of common stock | 50,000 | |||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of redeemable convertible preferred stock, net of issuance costs | ||||||||||||||||||||||||||||||||||||||||||||||||
unpaid follow-on offering issuance costs | 55,000 | |||||||||||||||||||||||||||||||||||||||||||||||
gain on extinguishment of debt and other liabilities | ||||||||||||||||||||||||||||||||||||||||||||||||
amortization of debt issuance costs | ||||||||||||||||||||||||||||||||||||||||||||||||
other assets | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from sale of available for sale securities | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of 2012 series x preferred stock, net of issuance costs | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from receipt of payment on promissory notes issued in exchange for shares of common stock | 0 | |||||||||||||||||||||||||||||||||||||||||||||||
reclassification of 2012 series x preferred stock from debt to preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||
conversion of 2012 series x preferred stock into series c preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from maturities of short-term investments | 1,245,000 | 5,500,000 | ||||||||||||||||||||||||||||||||||||||||||||||
purchases of investments | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||
preferred stock issuance costs | ||||||||||||||||||||||||||||||||||||||||||||||||
initial public offering issuance costs | -1,159,793 | -9,199,504 | ||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of 2012 series x preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of common stock | 911 | 114,954,000 | ||||||||||||||||||||||||||||||||||||||||||||||
issuance of series a preferred stock in settlement of convertible notes | ||||||||||||||||||||||||||||||||||||||||||||||||
amortization of debt discount and interest expense | ||||||||||||||||||||||||||||||||||||||||||||||||
gain on cancellation of preferred stock future tranche rights | ||||||||||||||||||||||||||||||||||||||||||||||||
issuance of 2007 series x preferred stock for licensing agreement | ||||||||||||||||||||||||||||||||||||||||||||||||
purchases of property and equipment | -141,956 | |||||||||||||||||||||||||||||||||||||||||||||||
proceeds from sale of short-term investments | ||||||||||||||||||||||||||||||||||||||||||||||||
purchases of short-term investments | ||||||||||||||||||||||||||||||||||||||||||||||||
debt issuance costs | ||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of convertible debt | ||||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of 2007 series x preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||
book value of assets transferred in distribution of subsidiary | ||||||||||||||||||||||||||||||||||||||||||||||||
book value of liabilities transferred in distribution of subsidiary | ||||||||||||||||||||||||||||||||||||||||||||||||
exchange of convertible debt |