7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 
      
    		                                                  
      assets
    		                                                  
      current assets:
    		                                                  
      cash and cash equivalents
    		92,710,000 80,871,000 78,964,000 76,247,000 253,730,000 84,518,000 118,764,000 88,205,000 64,333,000 84,753,000 104,139,000 139,259,000 122,449,000 88,543,000 80,026,000 203,126,000 400,224,000 969,124,000 1,888,025,000 127,436,000 104,855,000 295,858,000 89,093,000 80,931,000 81,709,000 83,580,000 103,443,000 70,502,000 156,478,000 210,323,000 364,469,000 102,724,000 132,741,000 138,717,000 200,278,000 160,754,000 285,502,000 234,048,000 39,035,000 71,764,000 80,048,000 72,533,000 35,256,000 14,031,000 70,049,000 108,247,000 32,837,000 71,560,000 106,011,000 77,481,000 
      marketable securities
    		860,150,000 858,066,000 814,411,000 817,463,000 751,027,000 485,374,000 479,227,000 688,723,000 583,155,000 617,813,000 635,062,000 643,860,000 605,231,000 730,766,000 843,503,000 816,892,000 865,833,000 703,864,000 447,578,000 445,493,000 500,684,000 494,270,000 439,528,000 483,946,000 370,188,000 411,810,000 421,114,000 514,800,000 513,414,000 506,582,000 417,981,000 321,212,000 375,187,000 447,325,000 279,480,000 380,560,000 293,595,000 231,321,000 273,859,000 245,238,000 272,317,000 297,261,000 309,450,000 328,034,000 149,921,000 130,233,000 129,432,000 95,209,000 88,945,000 21,794,000 
      accounts receivable
    		5,029,000 4,986,000 3,344,000 4,109,000 3,118,000 3,762,000 3,453,000 2,810,000 1,176,000 2,251,000 1,778,000 2,206,000 1,818,000 1,598,000 540,000     21,328,000 18,989,000 12,023,000 11,813,000 8,952,000 7,106,000 7,147,000 4,355,000 5,076,000 2,631,000                      
      inventory
    		32,034,000 30,848,000 29,605,000 27,616,000 26,429,000 23,937,000 23,070,000 19,076,000 17,274,000 15,671,000 11,374,000 8,492,000 5,176,000 4,060,000 2,485,000     14,698,000 11,371,000 11,231,000 9,778,000 7,331,000 5,849,000 4,659,000 2,328,000 869,000 863,000                      
      prepaid expenses and other current assets
    		43,186,000 44,693,000 42,292,000 40,165,000 39,885,000 34,536,000 39,113,000 35,021,000 38,414,000 36,751,000 39,303,000 38,955,000 46,487,000 42,336,000 43,226,000 39,835,000 32,238,000 21,443,000 19,511,000 23,651,000 28,861,000 26,959,000 29,152,000 24,177,000 19,985,000 19,063,000 19,696,000 17,167,000 16,458,000 15,538,000 15,614,000 17,486,000 15,316,000 13,018,000 12,391,000 10,264,000 10,277,000 8,923,000 9,190,000 8,728,000 7,225,000 4,602,000 5,512,000 4,814,000 4,990,000 2,842,000 3,033,000 2,502,000 2,616,000 2,011,000 
      total current assets
    		1,033,109,000 1,019,464,000 968,616,000 965,600,000 1,074,189,000 632,127,000 663,627,000 833,835,000 704,352,000 757,239,000 791,656,000 832,772,000 784,935,000 870,007,000 975,145,000 1,064,231,000 1,305,285,000 1,702,562,000 2,355,114,000 636,677,000 669,086,000 846,355,000 587,274,000 611,704,000 490,144,000 533,705,000 557,095,000 613,780,000 695,542,000 753,782,000 802,993,000 445,261,000 528,307,000 604,681,000 506,866,000 559,892,000 600,943,000 484,159,000 329,469,000 337,329,000 371,660,000 390,152,000 364,141,000 359,546,000 247,560,000 245,163,000 172,417,000 169,747,000 198,818,000 102,533,000 
      operating lease assets
    		33,650,000 36,785,000 39,861,000 42,879,000 45,841,000 48,750,000 51,606,000 54,409,000 57,162,000 59,866,000 62,521,000 65,129,000 67,692,000 70,214,000 72,688,000 75,124,000 77,532,000 79,901,000 82,244,000 84,661,000 86,952,000 89,208,000 91,440,000 93,643,000 95,833,000 98,500,000 57,768,000                        
      property and equipment
    		10,675,000 10,579,000 11,067,000 11,675,000 11,819,000 12,726,000 14,119,000 15,382,000 16,785,000 19,634,000 21,438,000 22,987,000 25,438,000 27,382,000 29,195,000 28,923,000 25,342,000 27,056,000 28,976,000 32,291,000 33,495,000 33,925,000 33,840,000 31,472,000 24,060,000 23,016,000 23,974,000 24,320,000 24,613,000 24,134,000 23,732,000 24,431,000 24,019,000 24,771,000 24,139,000 25,337,000 26,261,000 25,134,000 22,950,000 23,220,000 21,127,000 19,328,000 14,297,000 6,386,000 3,677,000 3,210,000 3,452,000 3,758,000 3,551,000 3,818,000 
      other non-current assets
    		3,930,000 3,942,000 4,721,000 4,724,000 4,056,000 4,056,000 4,056,000 4,057,000 4,057,000 4,057,000 3,956,000 3,956,000 3,903,000 3,955,000 2,900,000 2,900,000 2,900,000 2,900,000  1,125,000       60,000 238,000 416,000 595,000 1,104,000 891,000 1,070,000 1,249,000 2,888,000 1,615,000 1,339,000              
      total assets
    		1,385,705,000 1,471,237,000 1,555,518,000 1,663,199,000 1,791,794,000 773,063,000 849,709,000 937,118,000 1,007,258,000 1,085,153,000 1,151,298,000 1,238,718,000 1,180,320,000 1,252,467,000 1,335,859,000 1,437,736,000 1,541,498,000 1,874,603,000 2,488,434,000 852,952,000 908,449,000 976,141,000 799,738,000 890,741,000 698,616,000 783,870,000 822,131,000 858,457,000 929,079,000 998,235,000 1,040,126,000 614,397,000 687,200,000 760,600,000 557,316,000 619,094,000 672,042,000 557,601,000 396,117,000 420,065,000 449,086,000 474,383,000 474,336,000 491,904,000 269,608,000 272,030,000 181,912,000 201,205,000 219,069,000 111,252,000 
      liabilities and stockholders’ equity
    		                                                  
      current liabilities:
    		                                                  
      accounts payable
    		19,553,000 17,532,000 13,726,000 16,643,000 17,143,000 10,035,000 11,155,000 9,780,000 13,271,000 11,626,000 8,662,000 18,616,000 10,415,000 7,790,000 11,551,000 16,700,000 10,308,000 7,654,000 51,224,000 26,844,000 12,853,000 15,461,000 18,707,000 21,896,000 21,511,000 15,435,000 12,413,000 17,880,000 16,616,000 17,320,000 17,932,000 22,767,000 17,899,000 23,409,000 16,152,000 17,106,000 15,424,000 18,448,000 13,746,000 14,748,000 8,971,000 8,914,000 12,640,000 11,067,000 6,225,000 5,388,000 4,411,000 3,678,000 2,140,000 3,038,000 
      accrued expenses
    		37,217,000 35,289,000 20,761,000 46,861,000 33,307,000 36,742,000 25,129,000 43,167,000 30,490,000 29,189,000 22,459,000 30,350,000 29,756,000 28,383,000 19,747,000 31,967,000 29,234,000 36,054,000 23,601,000 60,140,000 49,724,000 41,911,000 39,631,000 53,142,000 46,750,000 49,218,000 37,199,000 42,147,000 25,303,000 25,793,000 17,005,000 34,031,000 30,760,000 29,641,000 25,114,000 32,002,000 22,808,000 14,414,000 12,247,000 15,996,000 15,985,000 11,584,000 15,604,000 14,020,000 10,004,000 5,456,000 3,841,000 6,586,000 4,764,000 3,586,000 
      income taxes payable
    		  683,000 871,000 52,682,000                                           1,462,000 5,257,000 5,141,000 
      operating lease liabilities
    		17,987,000 17,589,000 17,196,000 16,781,000 16,319,000 15,860,000 15,407,000 15,008,000 14,664,000 14,326,000 13,992,000 13,663,000 13,342,000 12,056,000 11,744,000 10,828,000 9,883,000 8,932,000 7,988,000 7,093,000 6,881,000 6,672,000 6,466,000 6,642,000 7,298,000 6,397,000 9,128,000                        
      total current liabilities
    		74,757,000 70,410,000 52,366,000 81,156,000 119,451,000 62,637,000 51,691,000 67,955,000 58,425,000 55,141,000 45,113,000 62,629,000 53,596,000 48,396,000 45,792,000 59,826,000 57,896,000 60,649,000 96,504,000 94,394,000 69,771,000 64,353,000 69,858,000 92,886,000 92,432,000 89,504,000 80,907,000 93,503,000 84,746,000 84,870,000 74,699,000 94,941,000 88,112,000 93,648,000 82,429,000 88,433,000 78,003,000 67,264,000 45,055,000 52,888,000 49,756,000 45,198,000 36,379,000 61,089,000 35,084,000 44,638,000 34,081,000 36,930,000 37,377,000 36,979,000 
      operating lease liabilities, net of current portion
    		26,528,000 31,171,000 35,744,000 40,207,000 44,515,000 48,760,000 52,940,000 56,988,000 60,834,000 64,620,000 68,346,000 71,996,000 75,499,000 78,946,000 82,338,000 85,659,000 88,840,000 91,971,000 95,052,000 97,458,000 99,693,000 101,874,000 104,010,000 106,074,000 108,096,000 110,073,000 66,006,000                        
      other non-current liabilities
    		90,000 101,000 880,000 880,000 1,156,000 1,156,000 1,156,000 1,156,000 1,156,000 1,156,000 1,313,000 3,279,000 1,055,000 1,055,000                                2,000 3,000  262,000  
      total liabilities
    		101,375,000 101,682,000 88,990,000 122,243,000 165,122,000 112,553,000 105,787,000 126,099,000 120,415,000 120,917,000 114,772,000 137,904,000 130,150,000 128,397,000 128,406,000 145,761,000 146,736,000 152,787,000 191,804,000 453,452,000 427,997,000 417,676,000 174,439,000 250,213,000 250,325,000 251,193,000 201,874,000 170,920,000 168,866,000 175,093,000 174,532,000 238,894,000 237,394,000 251,608,000                 
      stockholders’ equity:
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2025 and december 31, 2024
    		                                                  
      common stock
    		74,000 74,000 74,000 73,000 73,000 73,000 73,000 72,000 72,000 72,000 72,000 71,000 71,000 71,000 71,000 71,000 71,000 70,000 70,000 69,000 69,000 69,000 69,000 68,000 59,000 59,000 59,000 58,000 58,000 58,000 58,000 49,000 49,000 48,000 42,000 42,000 42,000 38,000 38,000 38,000 38,000 37,000 37,000 37,000 35,000 34,000 32,000 31,000 31,000 4,000 
      additional paid-in capital
    		2,538,357,000 2,521,545,000 2,506,788,000 2,493,811,000 2,478,066,000 2,464,284,000 2,451,620,000 2,436,523,000 2,421,862,000 2,410,905,000 2,398,930,000 2,386,325,000 2,374,755,000 2,362,327,000 2,351,147,000 2,334,348,000 2,322,460,000 2,306,304,000 2,265,713,000 2,242,801,000 2,225,538,000 2,203,599,000 2,181,517,000 2,156,363,000 1,861,523,000 1,839,710,000 1,818,393,000 1,794,283,000 1,775,113,000 1,743,657,000 1,717,609,000 1,174,904,000 1,160,048,000 1,142,233,000 857,107,000 842,013,000 828,043,000 652,574,000 640,124,000 630,078,000 619,451,000 607,708,000 598,494,000 591,334,000 347,947,000 344,490,000 246,970,000 244,881,000 243,601,000 2,836,000 
      accumulated other comprehensive income
    		2,051,000 655,000 365,000  3,420,000           -1,198,000 -198,000 -144,000 -3,000 105,000 663,000 1,636,000 74,000 202,000 464,000 490,000           29,000 297,000 89,000  225,000 222,000 191,000 -57,000 51,000 12,000 33,000 14,000 25,000  
      treasury stock
    		-802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -802,486,000 -783,438,000 -529,047,000                                 
      accumulated deficit
    		-453,666,000 -350,233,000 -238,213,000 -148,924,000 -52,401,000 -1,000,316,000 -904,198,000 -822,649,000 -726,709,000 -635,385,000 -551,579,000 -470,561,000 -507,087,000 -425,340,000 -333,534,000 -238,760,000 -144,133,000 -55,367,000  -1,843,475,000 -1,745,818,000 -1,646,839,000 -1,556,361,000 -1,516,105,000 -1,413,755,000 -1,307,582,000 -1,197,711,000 -1,104,633,000 -1,012,839,000 -918,175,000 -849,430,000 -798,061,000 -709,776,000 -632,639,000 -549,557,000 -483,151,000 -426,665,000 -363,831,000 -307,878,000 -284,680,000 -244,057,000 -203,802,000 -171,905,000 -166,948,000 -140,284,000 -143,988,000 -125,692,000 -113,444,000 -101,062,000 -89,885,000 
      total stockholders’ equity
    		1,284,330,000 1,369,555,000 1,466,528,000 1,540,956,000 1,626,672,000 660,510,000 743,922,000 811,019,000 886,843,000 964,236,000 1,036,526,000 1,100,814,000 1,050,170,000 1,124,070,000 1,207,453,000 1,291,975,000 1,394,762,000 1,721,816,000 2,296,630,000 399,500,000 480,452,000 558,465,000 625,299,000 640,528,000 448,291,000 532,677,000 620,257,000 687,537,000 760,213,000 823,142,000 865,594,000 375,503,000 449,806,000 508,992,000 307,380,000 358,591,000 401,449,000 289,078,000 332,373,000 345,118,000 375,657,000 404,165,000 426,817,000 424,366,000 207,749,000 200,548,000 121,343,000 131,482,000 142,595,000  
      total liabilities and stockholders’ equity
    		1,385,705,000 1,471,237,000 1,555,518,000 1,663,199,000 1,791,794,000 773,063,000 849,709,000 937,118,000 1,007,258,000 1,085,153,000 1,151,298,000 1,238,718,000 1,180,320,000 1,252,467,000 1,335,859,000 1,437,736,000 1,541,498,000 1,874,603,000 2,488,434,000 852,952,000 908,449,000 976,141,000 799,738,000 890,741,000 698,616,000 783,870,000 822,131,000 858,457,000 929,079,000 998,235,000 1,040,126,000 614,397,000 687,200,000 760,600,000 557,316,000 619,094,000 672,042,000 557,601,000 396,117,000 420,065,000 449,086,000 474,383,000 474,336,000 491,904,000 269,608,000 272,030,000 181,912,000    
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2025 and december 31, 2024
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2025 and december 31, 2024
    		                                                  
      commitments and contingent liabilities
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2024 and 2023
    		                                                  
      accumulated other comprehensive loss
    		   -1,518,000  -1,045,000 -1,087,000 -441,000 -5,896,000 -8,870,000 -8,411,000 -12,535,000 -15,083,000 -10,502,000 -7,745,000            -484,000 -2,171,000 -2,119,000 -2,398,000 -2,643,000 -1,389,000 -515,000 -650,000 -212,000 -313,000    -318,000          -5,000 
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2024 and december 31, 2023
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2024 and december 31, 2023
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2024 and december 31, 2023
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2023 and 2022
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2023 and december 31, 2022
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2023 and december 31, 2022
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2023 and december 31, 2022
    		                                                  
      other receivable
    		            3,774,000 2,704,000 5,365,000 4,378,000 6,990,000 8,131,000                                 
      financing lease assets
    		             64,000 95,000 183,000 300,000 871,000 502,000 590,000 677,000 793,000 881,000 993,000                           
      financing lease liabilities
    		            83,000 167,000 250,000 331,000 412,000 839,000 321,000 317,000 313,000 309,000 306,000 273,000                           
      financing lease liabilities, net of current portion
    		              276,000 276,000  167,000 248,000 331,000 412,000 491,000 571,000 673,000                           
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2022 and 2021
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2022 and december 31, 2021
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2022 and december 31, 2021
    		                                                  
      deferred revenue
    		              2,500,000                                 25,072,000 25,072,000 25,072,000 
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2022 and december 31, 2021
    		                                                  
      current assets of discontinued operations
    		                                                  
      non-current assets of discontinued operations
    		                                                  
      current liabilities of discontinued operations
    		                                                  
      non-current liabilities of discontinued operations
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2021 and 2020
    		                                                  
      taxes payable
    		                8,059,000 7,170,000 13,370,000                                
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2021 and december 31, 2020
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2021 and december 31, 2020
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2021 and december 31, 2020
    		                                                  
      retained earnings
    		                  30,850,000                                
      collaboration receivable – related party
    		                   2,123,000 2,334,000 2,537,000 2,577,000 1,539,000 1,838,000 2,524,000 2,319,000 2,462,000 3,395,000 19,326,000 3,512,000 2,448,000 3,489,000 4,842,000 11,265,000 4,886,000 8,182,000 7,853,000 6,814,000 8,225,000 9,078,000 10,474,000 7,017,000 6,492,000 18,759,000      
      collaboration receivable – other
    		                   1,948,000 1,992,000 1,827,000 2,033,000 1,928,000 869,000 2,222,000 1,640,000 670,000 440,000 440,000                     
      royalty receivable – related party
    		                     1,650,000 3,300,000 2,900,000 2,600,000 2,700,000 2,200,000 2,234,000 1,863,000 1,573,000 1,417,000 1,222,000 715,000                  
      deferred revenue – related party
    		                      4,748,000 10,933,000 16,873,000 18,454,000 22,167,000 32,710,000 42,141,000 41,132,000 39,212,000 37,842,000 35,867,000 37,069,000 37,690,000 35,913,000 36,415,000 31,469,000 16,523,000 19,665,000 22,650,000 22,608,000 6,886,000 35,686,000 18,847,000      
      deferred revenue, net of current portion – related party
    		                       50,580,000 49,797,000 51,616,000 54,961,000 59,809,000 66,294,000 72,408,000 81,831,000 125,798,000 134,202,000 141,957,000 150,596,000 154,297,000 173,941,000 183,540,000 1,949,000 4,699,000 6,240,000 9,389,000 133,000 2,725,000 26,352,000 26,697,000     
      liability related to the sale of future revenue, net of debt issuance costs
    		                   261,269,000 258,121,000 250,958,000                             
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2020 and 2019
    		                                                  
      other assets
    		                    1,350,000 1,575,000 1,800,000               1,382,000 838,000 611,000 678,000 660,000 640,000 590,000 454,000 455,000 467,000 4,000 11,000 1,624,000 
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2020 and december 31, 2019
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2020 and december 31, 2019
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2020 and december 31, 2019
    		                                                  
      deferred rent
    		                           766,000 686,000 625,000 550,000 301,000 3,586,000 3,529,000 3,473,000 3,412,000 3,356,000 2,933,000 2,539,000 2,479,000 2,150,000 2,092,000 1,245,000 310,000  142,000 133,000 123,000  104,000 
      deferred rent, net of current portion
    		                           17,608,000 17,826,000 17,815,000 18,002,000 18,155,000 15,080,000 16,003,000 16,911,000 17,773,000 18,649,000 17,719,000 16,740,000 17,360,000 17,433,000 15,631,000 11,007,000 3,724,000 423,000 145,000 186,000 220,000  288,000 
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2019 and 2018
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2019 and december 31, 2018
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2019 and december 31, 2018
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2019 and december 31, 2018
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2018 and 2017
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2018 and december 31, 2017
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2018 and december 31, 2017
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2018 and december 31, 2017
    		                                                  
      tenant improvement and other receivables
    		                               169,000 859,000 779,000 3,452,000 3,428,000 3,387,000 2,014,000 571,000 3,374,000 2,992,000 5,282,000 6,906,000        
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2017 and 2016
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2017 and december 31, 2016
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2017 and december 31, 2016
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2017 and december 31, 2016
    		                                                  
      commitments and contingencies
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2016 and 2015
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at september 30, 2016 and december 31, 2015
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at june 30, 2016 and december 31, 2015
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2016 and december 31, 2015
    		                                                  
      refundable income taxes
    		                                           3,841,000 3,841,000 3,841,000 4,496,000    
      other current liabilities
    		                                          4,000 6,000 8,000 8,000 624,000  144,000  
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2015 and 2014
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at march 31, 2015 and december 31, 2014
    		                                                  
      other receivables
    		                                           2,334,000       
      restricted cash
    		                                             571,000 571,000 571,000 571,000 571,000 
      preferred stock, 0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at december 31, 2014 and 2013
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized; no shares issued and outstanding
    		                                                  
      unbilled collaboration receivable – related party
    		                                                  
      deferred revenue– related party
    		                                             33,644,000     
      unbilled collaboration receivable—related party
    		                                              2,619,000    
      deferred revenue—related party
    		                                              25,072,000    
      deferred revenue, net of current portion—related party
    		                                              26,299,000    
      unbilled collaboration receivable
    		                                               476,000   
      deferred tax assets
    		                                                1,246,000 1,247,000 
      liabilities, convertible preferred stock, and stockholders’ equity
    		                                                  
      restricted stock liability
    		                                               9,000  38,000 
      deferred revenue, net of current portion
    		                                               32,567,000 38,835,000 45,103,000 
      restricted stock liability, net of current portion
    		                                               6,000  10,000 
      series a convertible preferred stock, 0.001 par value; no shares and 33,188,889 shares authorized, issued and outstanding at december 31, 2013 and 2012, respectively
    		                                                  
      series b convertible preferred stock, 0.001 par value; no shares and 5,190,551 shares authorized, issued and outstanding at december 31, 2013 and 2012, respectively
    		                                                  
      series c convertible preferred stock, 0.001 par value; no shares and 15,882,389 shares authorized, issued and outstanding at december 31, 2013 and 2012, respectively
    		                                                  
      stockholders’ equity
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 and no shares authorized at december 31, 2013 and 2012, respectively, no shares issued and outstanding.
    		                                                  
      total liabilities, convertible preferred stock, and stockholders’ equity
    		                                               201,205,000 219,069,000  
      deferred tax assets, net of current portion
    		                                                2,706,000 2,706,000 
      liabilities, convertible preferred stock, and stockholders’ deficit
    		                                                  
      series a convertible preferred stock, 0.001 par value; 0 and 33,188,889 shares authorized, issued and outstanding at september 30, 2013 and december 31, 2012, respectively; aggregate liquidation preference of 0 and 40,973 at september 30, 2013 and december 31, 2012, respectively
    		                                                  
      series b convertible preferred stock, 0.001 par value; 0 and 5,190,551 shares authorized, issued and outstanding at september 30, 2013 and december 31, 2012, respectively; aggregate liquidation preference of 0 and 10,232 at september 30, 2013 and december 31, 2012, respectively
    		                                                  
      series c convertible preferred stock, 0.001 par value; 0 and 15,882,389 shares authorized, issued and outstanding at september 30, 2013 and december 31, 2012, respectively; aggregate liquidation preference of 0 and 83,252 at september 30, 2013 and december 31, 2012, respectively
    		                                                  
      preferred stock, 0.001 par value; 25,000,000 shares authorized at september 30, 2013 and none authorized at december 31, 2012; none issued and outstanding at september 30, 2013
    		                                                  
      series a convertible preferred stock, 0.001 par value; 33,188,889 shares authorized, issued and outstanding at june 30, 2013 and december 31, 2012; aggregate liquidation preference of 41,969 and 40,973 at june 30, 2013 and december 31, 2012, respectively
    		                                                 32,940,000 
      series b convertible preferred stock, 0.001 par value; 5,190,551 shares authorized, issued and outstanding at june 30, 2013 and december 31, 2012; aggregate liquidation preference of 10,491 and 10,232 at june 30, 2013 and december 31, 2012, respectively
    		                                                 5,681,000 
      series c convertible preferred stock, 0.001 par value; 15,882,389 shares authorized, issued and outstanding at june 30, 2013 and december 31, 2012; aggregate liquidation preference of 85,592 and 83,252 at june 30, 2013 and december 31, 2012, respectively
    		                                                 77,301,000 
      stockholders’ deficit:
    		                                                  
      total stockholders’ deficit
    		                                                 -87,050,000 
      total liabilities, convertible preferred stock, and stockholders’ deficit
    		                                                 111,252,000 
      collaboration revenue
    		                                                 6,268,000 
      grant revenue
    		                                                  
      total revenue
    		                                                 6,268,000 
      operating expenses:
    		                                                  
      research and development
    		                                                 12,958,000 
      general and administrative
    		                                                 1,836,000 
      total operating expenses
    		                                                 14,794,000 
      income from operations
    		                                                 -8,526,000 
      interest income
    		                                                 5,000 
      income before benefit for income taxes
    		                                                 -8,521,000 
      benefit for income taxes
    		                                                 99,000 
      net income
    		                                                 -8,620,000 
      cumulative preferred stock dividends
    		                                                 -1,798,000 
      net income applicable to common stockholders
    		                                                 -10,418,000 
      net income per share
    		                                                 -2,800 
      weighted-average number of common shares used in net income per share applicable to common stockholders – basic and diluted
    		                                                 3,722,963,000 
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.