7Baggers

AstraZeneca PLC
(NASDAQ:AZN) 

AZN stock logo

AstraZeneca PLC discovers, develops, manufactures, and commercializes prescription medicines in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infection, neuroscience, and gastroenterology worldwide. The company's marketed products include Tagrisso, Lynparza, Imfinzi, Enhe...

Founded: 1999
Full Time Employees: 70,600
CEO: Pascal Soriot  
Sector: Healthcare
Industry: Drug Manufacturers-General

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At a glance:
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Quarterly
Annual
    Unit: USD2020-04-29 2020-02-14 2019-10-24 2019-06-30 2019-04-26 2019-02-14 2018-07-26 2018-02-02 2017-11-09 2017-07-27 2017-04-27 2017-02-02 2016-12-31 2016-11-10 
                  
      total revenue
    6,354,000,000 24,384,000,000 17,720,000,000 11,314,000,000 5,491,000,000 22,090,000,000 10,333,000,000 22,465,000,000 16,688,000,000 10,456,000,000 5,405,000,000 23,002,000,000 -17,416,999,756 17,417,000,000 
      yoy
    15.72% 10.38% 71.49% -49.64% -67.10% 111.27% 91.17% -2.33% -195.81% -39.97%     
      qoq
    -73.94% 37.61% 56.62% 106.05% -75.14% 113.78% -54.00% 34.62% 59.60% 93.45% -76.50% -232.07% -200.00%  
      product sales
    6,311,000,000 23,565,000,000 17,315,000,000 11,183,000,000 5,465,000,000 21,049,000,000 10,015,000,000 20,152,000,000 14,665,000,000 9,783,000,000 4,843,000,000 21,319,000,000 -16,059,000,387 16,059,000,000 
      collaboration revenue
    43,000,000 819,000,000 405,000,000 131,000,000 26,000,000          
      cost of sales
    -1,420,000,000 -4,921,000,000 -3,543,000,000  -1,129,000,000 -4,936,000,000  -4,318,000,000 -3,093,000,000 -1,844,000,000 -894,000,000 -4,126,000,000 2,966,000,700 -2,966,000,000 
      gross profit
    4,934,000,000 19,463,000,000 14,177,000,000 9,122,000,000 4,362,000,000 17,154,000,000 8,187,000,000 18,147,000,000 13,595,000,000 8,612,000,000 4,511,000,000 18,876,000,000 -14,450,999,056 14,451,000,000 
      yoy
    13.11% 13.46% 73.16% -49.73% -67.91% 99.19% 81.49% -3.86% -194.08% -40.41%     
      qoq
    -74.65% 37.29% 55.42% 109.12% -74.57% 109.53% -54.89% 33.48% 57.86% 90.91% -76.10% -230.62% -200.00%  
      gross margin %
    77.65% 79.82% 80.01% 80.63% 79.44% 77.66% 79.23% 80.78% 81.47% 82.36% 83.46% 82.06% 82.97% 82.97% 
      distribution costs
    -87,000,000 -339,000,000 -247,000,000  -78,000,000 -331,000,000  -310,000,000 -225,000,000 -149,000,000 -77,000,000 -326,000,000 242,999,944 -243,000,000 
      research and development expense
    -1,388,000,000 -6,059,000,000 -3,968,000,000  -1,266,000,000 -5,932,000,000  -5,757,000,000 -4,206,000,000 -2,802,000,000 -1,453,000,000 -5,890,000,000 4,346,999,150 -4,347,000,000 
      selling, general and administrative costs
    -2,719,000,000 -11,682,000,000 -8,656,000,000  -2,514,000,000 -10,031,000,000  -10,233,000,000 -7,155,000,000 -4,658,000,000 -2,300,000,000 -9,413,000,000 8,027,001,008 -8,027,000,000 
      other operating income and expense
    480,000,000 1,541,000,000 1,041,000,000 706,000,000 593,000,000 2,527,000,000  1,830,000,000 982,000,000 839,000,000 236,000,000 1,655,000,000 -534,998,811 535,000,000 
      operating profit
    1,220,000,000 2,924,000,000 2,347,000,000 1,590,000,000 1,097,000,000 3,387,000,000 1,459,000,000 3,677,000,000 2,991,000,000 1,842,000,000 917,000,000 4,902,000,000 -2,368,997,765 2,369,000,000 
      yoy
    11.21% -13.67% 60.86% -56.76% -63.32% 83.88% 59.11% -24.99% -226.26% -22.25%     
      qoq
    -58.28% 24.58% 47.61% 44.94% -67.61% 132.15% -60.32% 22.94% 62.38% 100.87% -81.29% -306.92% -200.00%  
      operating margin %
    19.20% 11.99% 13.24% 14.05% 19.98% 15.33% 14.12% 16.37% 17.92% 17.62% 16.97% 21.31% 13.60% 13.60% 
      finance income
    51,000,000 172,000,000 133,000,000 96,000,000 55,000,000 138,000,000 78,000,000 113,000,000 71,000,000 39,000,000 18,000,000 67,000,000 11,000,000 44,000,000 
      finance expense
    -332,000,000 -1,432,000,000 -1,081,000,000  -367,000,000 -1,419,000,000  -1,508,000,000 -1,199,000,000 -781,000,000 -340,000,000 -1,384,000,000 -255,500,000 -1,022,000,000 
      share of after-tax losses in associates and joint ventures
     -116,000,000 -91,000,000  -27,000,000          
      profit before tax
    935,000,000 1,548,000,000 1,308,000,000 899,000,000 758,000,000 1,993,000,000 786,000,000 2,227,000,000 1,820,000,000 1,074,000,000 582,000,000 3,552,000,000 342,250,000 1,369,000,000 
      taxation
    -185,000,000 -321,000,000 -358,000,000  -195,000,000 57,000,000  641,000,000 -213,000,000 -116,000,000 -70,000,000 -146,000,000 55,000,000 220,000,000 
      profit for the period
    750,000,000 1,227,000,000 950,000,000 670,000,000 563,000,000 2,050,000,000 635,000,000 2,868,000,000 1,607,000,000 958,000,000 512,000,000 3,406,000,000 397,250,000 1,589,000,000 
      other comprehensive income
                  
      items that will not be reclassified to profit or loss
                  
      remeasurement of the defined benefit pension liability
    440,000,000 -364,000,000 -151,000,000  10,000,000 -46,000,000 187,000,000 -242,000,000 -146,000,000 -271,000,000 1,000,000 -575,000,000 -281,750,000 -1,127,000,000 
      net gains on equity investments measured at fair value through other comprehensive income
    171,000,000    120,000,000          
      fair value movements related to own credit risk on bonds designated as fair value through profit or loss
    21,000,000     8,000,000         
      tax on items that will not be reclassified to profit or loss
    -66,000,000 21,000,000 21,000,000 17,000,000 -43,000,000 56,000,000  16,000,000 23,000,000 71,000,000  136,000,000 64,000,000 256,000,000 
      items that may be reclassified subsequently to profit or loss
                  
      foreign exchange arising on consolidation
    -608,000,000 40,000,000 -385,000,000  53,000,000 -450,000,000  536,000,000 531,000,000 377,000,000 154,000,000 -1,050,000,000 -172,500,000 -690,000,000 
      foreign exchange arising on designating borrowings in net investment hedges
    -380,000,000 -252,000,000 -491,000,000  -180,000,000 -520,000,000  505,000,000 622,000,000 383,000,000 100,000,000 -591,000,000 -48,500,000 -194,000,000 
      fair value movements on cash flow hedges
    -187,000,000    -54,000,000 -37,000,000  311,000,000 226,000,000 127,000,000 7,000,000 -115,000,000 -6,500,000 -26,000,000 
      fair value movements on cash flow hedges transferred to profit or loss
    45,000,000    47,000,000 111,000,000 69,000,000 -315,000,000 -281,000,000 -200,000,000 -39,000,000 195,000,000 10,250,000 41,000,000 
      fair value movements on derivatives designated in net investment hedges
    60,000,000    3,000,000   -48,000,000 -39,000,000 -35,000,000 -30,000,000  -24,000,000 -96,000,000 
      costs of hedging
     -47,000,000 -35,000,000 3,000,000           
      tax on items that may be reclassified subsequently to profit or loss
    73,000,000 38,000,000 62,000,000 20,000,000 23,000,000 51,000,000 55,000,000 -33,000,000 -125,000,000 -70,000,000 24,000,000 86,000,000 15,750,000 63,000,000 
      other comprehensive loss for the period, net of tax
    -436,000,000 -611,000,000 -1,128,000,000            
      total comprehensive income for the period
    314,000,000 616,000,000  97,000,000 535,000,000 991,000,000 215,000,000 3,507,000,000   578,000,000 1,628,000,000 -14,250,000 -57,000,000 
      profit attributable to:
                  
      owners of the parent
    780,000,000 1,335,000,000 1,022,000,000 723,000,000 593,000,000 2,155,000,000 690,000,000 3,001,000,000 1,700,000,000 1,014,000,000 537,000,000 3,499,000,000 414,250,000 1,657,000,000 
      non-controlling interests
    -30,000,000 -108,000,000 -72,000,000  -30,000,000 -105,000,000  -133,000,000 -93,000,000 -56,000,000 -25,000,000 -93,000,000 -17,000,000 -68,000,000 
      total comprehensive income attributable to:
                  
      basic earnings per 0.25 ordinary share
    590,000 1,030,000 790,000 560,000 470,000 1,700,000 540,000 2,370,000 1,340,000 800,000 420,000 2,770,000 327,500 1,310,000 
      diluted earnings per 0.25 ordinary share
    590,000 1,030,000 790,000 560,000 470,000 1,700,000 540,000 2,370,000 1,340,000 800,000 420,000 2,760,000 327,500 1,310,000 
      weighted-average number of ordinary shares in issue
    1,312,000,000 1,301,000,000 1,297,000,000 1,289,000,000 1,267,000,000 1,267,000,000 1,267,000,000 1,266,000,000 1,266,000,000 1,266,000,000 1,265,000,000 1,265,000,000  1,265,000,000 
      diluted weighted-average number of ordinary shares in issue
    1,313,000,000 1,301,000,000 1,297,000,000 1,290,000,000 1,268,000,000 1,267,000,000 1,267,000,000 1,267,000,000 1,266,000,000 1,266,000,000 1,266,000,000 1,266,000,000  1,266,000,000 
      for the year ended 31 december
                  
      net incomees on equity investments measured at fair value through other comprehensive income
     -28,000,000    -171,000,000         
      fair-value movements related to own credit risk on bonds designated as fair-value through profit or loss
                  
      fair-value movements on cash flow hedges
     -101,000,000 -156,000,000            
      fair-value movements on cash flow hedges transferred to profit or loss
     52,000,000 109,000,000 14,000,000           
      fair-value movements on derivatives designated in net investment hedges
     35,000,000 35,000,000            
      amortisation of loss on cash flow hedge
         1,000,000  1,000,000 1,000,000 1,000,000  1,000,000 250,000 1,000,000 
      for the nine months ended 30 september
                  
      net (losses)/gains on equity investments measured at fair value through other comprehensive income
      -136,000,000            
      total comprehensive (loss)/income for the period
      -178,000,000            
      for the half year ended 30 june
                  
      other comprehensive income for the period, net of tax
        -28,000,000      66,000,000 -1,778,000,000 -411,500,000 -1,646,000,000 
      externalisation revenue
         1,041,000,000 318,000,000 2,313,000,000 2,023,000,000 673,000,000 562,000,000 1,683,000,000 -1,357,999,369 1,358,000,000 
      share of after tax losses in associates and joint ventures
         -113,000,000  -55,000,000 -43,000,000 -26,000,000 -13,000,000 -33,000,000 -5,500,000 -22,000,000 
      fair value movements on derivatives designated in net investment hedges costs of hedging
         -54,000,000         
      net available for sale losses taken to equity
             -94,000,000 -150,000,000    
      other comprehensive (loss)/income for the period, net of tax
         -1,059,000,000         
      other operating income & expense
          1,086,000,000        
      fair value movements on equity investments
          156,000,000        
      other comprehensive income/
                  
      net available for sale (losses)/gains taken to equity
           -83,000,000 -36,000,000      
      other comprehensive income/(loss) for the period, net of tax
           639,000,000 776,000,000 289,000,000     
      total comprehensive income/(loss) for the period
            2,383,000,000 1,247,000,000     
      total comprehensive income/(loss) attributable to:
                  
      net available for sale gains/(losses) taken to equity
               139,000,000 31,500,000 126,000,000 
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2025-11-06 2025-06-30 2025-02-06 2024-06-30 2024-04-25 2024-02-08 2023-11-02 2021-02-11 2020-04-29 2020-02-14 2019-10-24 2019-06-30 2019-04-26 2019-02-14 2018-07-26 2018-05-18 2018-02-14 2018-02-02 2017-11-09 2017-07-27 2017-04-27 2017-02-02 2016-11-10 2016-02-02 
                              
        assets
                              
        non-current assets
                              
        property, plant and equipment
      12,083 11,637 10,252 9,630 9,411 9,402 8,723 8,251 7,347,000,000 7,688 7,317,000,000 7,442 7,446,000,000 7,421 7,514 7,721 7,421,000,000 7,615 7,329,000,000 7,079 6,954 6,848 6,690 6,848,000,000 
        right-of-use assets
      1,700 1,592 1,395 1,203 1,205 1,100 977 666 644,000,000 647 690,000,000 702 707,000,000            
        goodwill
      21,219 21,222 21,025 21,060 19,978 20,048 19,939 11,845 11,569,000,000 11,668 11,595,000,000 11,668 11,674,000,000 11,707 11,717 11,834 11,707,000,000 11,825 11,841,000,000 11,774 11,688 11,658 11,806 11,658,000,000 
        intangible assets
      38,191 37,925 37,177 39,426 38,834 38,089 37,687 20,947 19,718,000,000 20,833 21,454,000,000 22,257 22,852,000,000 21,959 24,887 25,850 21,959,000,000 26,188 27,124,000,000 27,465 27,386 27,586 28,507 27,586,000,000 
        investments in associates and joint ventures
      296 276 268 264 130 147 62 39 44,000,000 58 43,000,000 73 76,000,000 89 157 187 89,000,000 103 78,000,000 86 88 99 95 99,000,000 
        other investments
      1,990 1,863 1,632 1,607 1,565 1,530 1,228 1,108 1,476,000,000 1,401 1,293,000,000 1,362 1,530,000,000 833 1,089 987 833,000,000 933 1,004,000,000 989 739 727 715 727,000,000 
        derivative financial instruments
      502 509 182 217 213 228 151 171 104,000,000 61 56,000,000 124 94,000,000 157 459 594 157,000,000 504 440,000,000 336 310 343 278 343,000,000 
        other receivables
      1,159 1,066 930 806 745 803 761 720 527,000,000 740 384,000,000 454 496,000,000 515 738 525 515,000,000 847 953,000,000 967 891 901 681 901,000,000 
        income tax receivable
      1,247 1,137 1,859 1,575 1,153 1,426 697 364 262,000,000 285 228,000,000 246 118,000,000 207 264 563 207,000,000  721,000,000 786 627 426 640 426,000,000 
        deferred tax assets
      6,129 6,256 5,347 4,734 4,618 4,718 4,057 3,438 2,960,000,000 2,718 2,554,000,000 2,588 2,531,000,000 2,379 2,334 2,401 2,379,000,000 2,189 2,184,000,000 2,125 1,266 1,102 1,584 1,102,000,000 
        current assets
                              
        inventories
      6,593 6,467 5,288 5,667 5,337 5,424 5,292 4,024 3,123,000,000 3,193 3,129,000,000 3,197 3,050,000,000 2,890 3,118 3,283 2,890,000,000 3,035 3,162,000,000 2,901 2,652 2,334 2,420 2,334,000,000 
        trade and other receivables
      14,338 14,168 12,972 11,047 11,072 12,126 11,300 7,022 5,080,000,000 5,761 5,279,000,000 5,319 5,289,000,000 5,574 5,257 5,444 5,574,000,000 5,009 4,540,000,000 4,348 4,686 4,573 5,449 4,573,000,000 
        cash and cash equivalents
      8,143 7,058 5,488 6,916 7,841 5,840 4,871 7,832 3,413,000,000 5,369 3,967,000,000 5,428 4,136,000,000 4,831 2,978 3,005 4,831,000,000 3,324 4,036,000,000 5,239 3,129 5,018 3,090 5,018,000,000 
        total assets
      114,456 112,422 104,035 104,340 102,293 101,119 96,086 66,729 57,211,000,000 61,377 58,906,000,000 61,889 61,055,000,000 60,651 61,344 63,281 60,651,000,000 63,354 64,587,000,000 65,119 60,959 62,526 63,222 62,526,000,000 
        liabilities
                              
        current liabilities
                              
        interest-bearing loans and borrowings
      -6,174 -6,492 -2,337 -5,067 -6,050 -5,129 -5,372 -2,194 -2,289,000,000 -1,822 -228,000,000  -3,544,000,000 -1,754  -4,170 -1,754,000,000 -2,247 -941,000,000 -2,933 -2,839 -2,307 -2,939 -2,307,000,000 
        lease liabilities
      -379 -361 -339 -292 -281 -271 -235 -192 -181,000,000 -188 -349,000,000  -175,000,000            
        trade and other payables
      -25,028 -23,986 -22,465 -20,463 -19,699 -22,374 -20,542 -15,785 -12,633,000,000 -13,987 -12,538,000,000  -13,102,000,000 -12,841  -11,481 -12,841,000,000 -11,641 -10,832,000,000 -10,072 -9,899 -10,486 -9,961 -10,486,000,000 
        provisions
      -1,176 -1,168 -1,269 -1,168 -1,148 -1,028 -1,193 -976 -649,000,000 -723 -401,000,000  -397,000,000 -506  -1,011 -506,000,000 -1,121 -1,167,000,000 -1,070 -1,044 -1,065 -936 -1,065,000,000 
        income tax payable
      -1,268 -1,429 -1,406 -1,525 -1,631 -1,584 -1,163 -1,127 -1,260,000,000 -1,361 -1,234,000,000  -1,010,000,000 -1,164  -1,462 -1,164,000,000  -1,513,000,000 -1,576 -1,646 -1,380 -1,534 -1,380,000,000 
        non-current liabilities
                              
        deferred tax liabilities
      -3,604 -3,615 -3,305 -3,333 -2,621 -2,844 -2,752 -2,918 -2,501,000,000 -2,490 -2,595,000,000  -3,267,000,000 -3,286  -3,987 -3,286,000,000 -3,995 -5,079,000,000 -4,944 -4,036 -3,956 -4,051 -3,956,000,000 
        retirement benefit obligations
      -1,271 -1,418 -1,330 -1,326 -1,280 -1,520 -1,048 -3,202 -2,129,000,000 -2,807 -2,392,000,000  -2,385,000,000 -2,511  -2,516 -2,511,000,000 -2,583 -2,490,000,000 -2,534 -2,171 -2,186 -2,870 -2,186,000,000 
        other payables
      -2,013 -1,600 -1,770 -2,208 -2,596 -2,660 -2,244 -6,084 -6,221,000,000 -6,291 -6,848,000,000  -6,875,000,000 -6,770  -7,963 -6,770,000,000 -7,840 -9,807,000,000 -9,371 -9,496 -9,488 -10,842 -9,488,000,000 
        total liabilities
      -68,485 -67,612 -63,164 -64,742 -64,792 -61,953 -58,865 -51,091 -44,995,000,000 -46,781 -45,237,000,000  -49,026,000,000 -46,607  -48,708 -46,607,000,000 -46,712 -49,140,000,000 -49,707 -46,180 -45,857 -48,310 -45,857,000,000 
        net assets
      45,971 44,810 40,871 39,598 37,501 39,166 37,221 15,638 12,216,000,000 14,596 13,669,000,000 15,071 12,029,000,000 14,044 14,272 14,573 14,044,000,000 16,642 15,447,000,000 15,412 14,779 16,669 14,912 16,669,000,000 
        equity
                              
        share capital
      388 388 388 388 388 388 387 328 328,000,000 328 328,000,000 328 317,000,000 317 317 317 317,000,000 317 316,000,000 316 316 316 316 316,000,000 
        share premium account
      35,243 35,238 35,226 35,199 35,194 35,188 35,166 7,971 7,946,000,000 7,941 7,919,000,000 7,911 4,438,000,000 4,427 4,409 4,407 4,427,000,000 4,393 4,381,000,000 4,374 4,368 4,351 4,344 4,351,000,000 
        other reserves
      2,044 2,070 2,012 2,078 2,075 2,065 2,078 2,024 2,056,000,000 2,046 2,052,000,000 2,044 2,046,000,000 2,041 2,040 2,027 2,041,000,000 2,029 2,027,000,000 2,033 2,042 2,047 2,031 2,047,000,000 
        retained earnings
      8,213 7,023 3,160 1,847 -212 1,502 -434 5,299 448,000,000 2,812 1,865,000,000 3,265 3,682,000,000 5,683 5,879 6,164 5,683,000,000 8,221 7,001,000,000 6,930 6,263 8,140 6,381 8,140,000,000 
        capital and reserves attributable to equity holders of the parent
      45,888 44,719                       
        non-controlling interests
      83 91 85 86 56 23 24 16 1,438,000,000 1,469 1,505,000,000 1,523 1,546,000,000 1,576 1,627 1,658 1,576,000,000 1,682 1,722,000,000 1,759 1,790 1,815 1,840 1,815,000,000 
        total equity
      45,971 44,810 40,871 39,598 37,501 39,166 37,221 15,638 12,216,000,000 14,596 13,669,000,000 15,071 12,029,000,000 14,044 14,272 14,573 14,044,000,000 16,642 15,447,000,000 15,412 14,779 16,669 14,912 16,669,000,000 
        ​
       83,483  78,947                     
        assets non-current assets
                              
        liabilities current liabilities
                              
        assets held for sale
              131,000,000 70    982   982,000,000      332  
        non-current assets - sum
                 46,670             
        current assets - sum
                 15,219             
        capital and reserves attributable to equity holders of the parent - sum
                 13,548             
        capital and reserves attributable to equity holders of the company
                              
        income tax receivables
                       524       
        income tax payables
                       -1,350       
        *31 march comparatives have been restated to reflect an adjustment to the acquisition-accounting for zs pharma (as detailed in note 25 of the astrazeneca annual report and form 20-f information 2016, page 174) and an adjustment to the acquisition-accounting for acerta pharma (as detailed in note 4 of the full year and fourth quarter 2016 results announcement).
                              
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2021-02-11 2020-02-14 2019-02-14 2018-05-18 2017-04-27 2017-02-02 
              
          cash flows from operating activities
              
          profit before tax
        3,916 1,548 1,993 374 582 2,183 
          finance income and expense
        1,219 1,260 1,281 308 322 339 
          share of after tax losses of associates and joint ventures
              
          depreciation, amortisation and impairment
        3,149 3,762 3,753 709 658 590 
          movement in working capital and short-term provisions
              
          gains on disposal of intangible assets
        -1,030 -1,243 -1,885 -65   
          fair value movements on contingent consideration arising from business combinations
        -272 -614 -495    
          non-cash and other movements
        -276 378 -290 -242 -349 53 
          cash generated from operations
        7,094 4,861 3,831 105 339 2,115 
          interest paid
        -733 -774 -676 -128 -189 -188 
          tax paid
        -1,562 -1,118 -537 -117 -62 33 
          net cash inflow from operating activities
        4,799 2,969 2,618  88 1,960 
          cash flows from investing activities
              
          acquisition of subsidiaries, net of cash acquired
              
          payment of contingent consideration from business combinations
        -822 -709 -349 -62   
          purchase of property, plant and equipment
        -961 -979 -1,043 -213 -286 -534 
          disposal of property, plant and equipment
        106 37 12 35 
          purchase of intangible assets
        -1,645 -1,481 -328 -121 -99 -107 
          disposal of intangible assets
        951 2,076 2,338 362 51 1,310 
          purchase of non-current asset investments
        -119 -13 -102  -18 -20 
          disposal of non-current asset investments
        1,381 18 24  
          movement in short-term investments, fixed deposits and other investing instruments
        745 194     
          payments to associates and joint ventures
         -74     
          disposal of investments in associates and joint ventures
              
          interest received
        47 124 193 33 45 35 
          net cash outflow from investing activities
        -285    -146 603 
          net cash inflow before financing activities
        4,514 2,312 3,581    
          cash flows from financing activities
              
          proceeds from issue of share capital
        30 3,525 34 14 17 
          own shares purchased by employee benefit trust
              
          payments to acquire non-controlling interests
              
          issue of loans and borrowings
              
          repayment of loans and borrowings
              
          dividends paid
        -3,572 -3,592 -3,484 -2,363 -2,368 
          hedge contracts relating to dividend payments
        -101 -67 -47 -32 
          repayment of obligations under leases
        -207 -186     
          movement in short-term borrowings
        288 -516 -98 1,733 352 -315 
          payment of acerta pharma share purchase liability
              
          net cash outflow from financing activities
        -2,203 -1,765 -2,044 -663 -2,042  
          net increase in cash and cash equivalents in the period
        2,311 547 1,537    
          cash and cash equivalents at the beginning of the period
        5,223 4,671 3,172 3,172 4,924 
          exchange rate effects
        12 -38 13 14 -22 
          cash and cash equivalents at the end of the period
        7,546 5,223 4,671 2,655 2,838 2,237 
          cash and cash equivalents consist of:
              
          cash and cash equivalents
        7,832 5,369 4,831 3,005 3,129 1,928 
          overdrafts
        -286 -146 -160 -350 -291 309 
          ​
              
          net cash (outflow)/inflow from financing activities
              
          payments upon vesting of employee share awards attributable to business combinations
              
          movement in profit-participation liability
        40      
          net cash inflow/(outflow) from financing activities
              
          share of after-tax losses of associates and joint ventures
        27 116     
          decrease in working capital and short-term provisions
        361    -887  
          issue of loans
        2,968 500 2,971    
          repayment of loans
        -1,609 -1,500 -1,400    
          reported operating profit
              
          increase in working capital and short-term provisions
         -346 -639 -993   
          taxation paid
              
          net cash inflow/(outflow) from operating activities
              
          net cash inflow/(outflow) before financing activities
           133   
          other investments
              
          cash and investments
              
          overdrafts and short-term borrowings
              
          lease liabilities
              
          current instalments of loans
              
          loans due after one year
              
          interest-bearing loans and borrowings
              
          net derivatives
              
          net debt
              
          for the year ended 31 december
              
          movement in profit-participation liability[80]
         150     
          net cash (outflow)/inflow from investing activities
         -657     
          leases[29]
              
          for the half year ended 30 june
              
          movement in short-term investments and fixed deposits
          405 436 357 -1 
          payments to joint ventures
          -187 -161  -22 
          net cash (outflow)/inflow before financing activities
              
          net cash outflow from operating activities
              
          leases[28]
              
          share of after tax losses in associates and joint ventures
          113 14 13 11 
          non-contingent payments on business combinations
              
          net cash inflow/(outflow) from investing activities
          963 273   
          repayment of obligations under finance leases
            -14 -4 
          net cash (outflow)/inflow from operating activities
           -140   
          net decrease in cash and cash equivalents in the period
           -530 -2,100 2,259 
          cash and cash equivalents consists of:
              
          net cash outflows from financing activities
              
          finance leases
              
          payments made by subsidiaries to non-controlling interests
             
          (increase)/decrease in working capital and short-term provisions
              
          (gains)/losses on disposal of intangible assets
              
          fair value movement on contingent consideration arising from business combinations
              
          cash, short-term investments and derivatives
              
          upfront payments on business acquisitions
              
          net cash outflow before financing activities
            -58  
          upfront payments on business combinations
              
          payment of contingent consideration on business combinations
            -213  
          new long term loans
             
          gain on disposal of intangible assets
              
          new long-term loans
             
          payment of contingent consideration on business acquisitions
              
          decrease/(increase) in working capital and short-term provisions